caa a22 4500 477089437 CHVBK 20180405111512.0 cr unu---uuuuu 170330e19960901xx s 000 0 eng 10.1007/BF02265051 doi (NATIONALLICENCE)springer-10.1007/BF02265051 Human chromosome 3: high-resolution fluorescence in situ hybridization mapping of 40 unique Not l linking clones homologous to genes and cDNAs [Elektronische Daten] [A. Protopopov, R. Gizatullin, N. Vorobieva, M. Protopopova, C. Kiss, V. Kashuba, G. Klein, L. Kisselev, A. Graphodatsky, E. Zabarovsky] Forty newNotl linking clones representing sequence tagged sites (STSs) were mapped by fluorescencein situ hybridization (FISH) to different regions of human chromosome 3 (HSA3). Clone NL1-245, containing human aminoacylase 1, was localized to 3p21.2-p21.1. Our previous localization of the CLC-2 chloride channel protein gene was refined to 3q27. Clone NL2-316 most likely contains a translocon-associated protein γ-subunit gene and was mapped to 3q23-q24. To our knowledge, this is the first time this gene has been mapped. OneNoti linking clone (NL1-229) probably contains a new protein phosphatase gene. This clone was mapped to 3p25. FiveNoti linking clones probably contain human expressed sequence tags (ESTs), as they possess sequences with a high level of identity (>90%) to cDNA clones. Other clones show 56-85% homology to known mammalian and human genes with various functions, including oncogenes and tumour-suppressor genes. These clones might represent new genes. Rapid Science Publishers, 1996 fluorescence in situ hybridization nationallicence human chromosome 3 nationallicence localization of genes nationallicence Not l linking clones nationallicence Protopopov A. Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia aut Gizatullin R. Department of Tumor Biology, Karolinska Institute, S-171 77, Stockholm, Sweden aut Vorobieva N. Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia aut Protopopova M. Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia aut Kiss C. Department of Tumor Biology, Karolinska Institute, S-171 77, Stockholm, Sweden aut Kashuba V. Department of Tumor Biology, Karolinska Institute, S-171 77, Stockholm, Sweden aut Klein G. Department of Tumor Biology, Karolinska Institute, S-171 77, Stockholm, Sweden aut Kisselev L. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia aut Graphodatsky A. Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia aut Zabarovsky E. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia aut Chromosome Research Kluwer Academic Publishers 4/6(1996-09-01), 443-447 0967-3849 4:6<443 1996 4 10577 https://doi.org/10.1007/BF02265051 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02265051 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Protopopov A. Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Gizatullin R. Department of Tumor Biology, Karolinska Institute, S-171 77, Stockholm, Sweden aut NATIONALLICENCE 700 1- Vorobieva N. Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Protopopova M. Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Kiss C. Department of Tumor Biology, Karolinska Institute, S-171 77, Stockholm, Sweden aut NATIONALLICENCE 700 1- Kashuba V. Department of Tumor Biology, Karolinska Institute, S-171 77, Stockholm, Sweden aut NATIONALLICENCE 700 1- Klein G. Department of Tumor Biology, Karolinska Institute, S-171 77, Stockholm, Sweden aut NATIONALLICENCE 700 1- Kisselev L. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Graphodatsky A. Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Zabarovsky E. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia aut NATIONALLICENCE 773 0- Chromosome Research Kluwer Academic Publishers 4/6(1996-09-01), 443-447 0967-3849 4:6<443 1996 4 10577 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer