caa a22 4500 477095380 CHVBK 20180405111526.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF00198325 doi (NATIONALLICENCE)springer-10.1007/BF00198325 Distribution of serotonin-immunoreactivity in the brain of the pigeon ( Columba livia ) [Elektronische Daten] [E. Challet, D. Miceli, J. Pierre, J. Repérant, G. Masicotte, M. Herbin, N. Vesselkin] The distribution of serotonin (5-HT)-containing perikarya, fibers and terminals in the brain of the pigeon (Columba livia) was investigated, using immunohistochemical and immunofluorescence methods combined with retrograde axonal transport. Twenty-one different groups of 5-HT immunoreactive (IR) cells were identified, 2 of which were localized at the hypothalamic level (periventricular organ, infundibular recess) and 19 at the tegmental-mesencephalic and rhombencephalic levels. Ten of the cell groups were situated within the region of the midline from the isthmic to the posterior rhombencephalic level and constituted the raphe system (nucleus annularis, decussatio brachium conjunctivum, area ventralis, external border of the nucleus interpeduncularis, zona peri-nervus oculomotorius, zona perifasciculus longitudinalis medialis, zona inter-flm, nucleus linearis caudalis, nucleus raphe superior pars ventralis, nucleus raphe inferior). The 9 other cell populations belonged to the lateral group and extended from the posterior mesencephalic tegmentum to the caudal rhombencephalon [formatio reticularis mesencephali, nucleus ventrolateralis tegmenti, ectopic area (Ec) of the nucleus isthmo-opticus (NIO), nucleus subceruleus, nucleus ceruleus, nucleus reticularis pontis caudalis, nucleus vestibularis medialis, nucleus reticularis parvocellularis and nucleus reticularis magnocellularis]. Combining the retrograde axonal transport of rhodamine β-isothiocyanate (RITC) after intraocular injection and immunohistofluorescence (fluoresceine isothiocyanate: FITC/5-HT) showed the centrifugal neurons (NIO, ec) to be immunonegative. Serotonin-IR fibers and terminals were found to be very broadly distributed within the brain and were particularly prominent in several structures of the telencephalon (archistriatum pars dorsalis, nucleus taeniae, area parahippocampalis, septum), diencephalon (nuclei preopticus medianus, magnocellularis, nucleus geniculatus lateralis pars ventralis, nucleus triangularis, nucleus pretectalis), mesencephalon-rhombencephalon (superficial layers of the optic tectum, nucleus ectomamillaris, nucleus isthmo-opticus and in most of the cranial nerve nuclei). Comparing the present results with those of previous studies in birds suggests some major serotonin containing pathways in the avian brain and clarifies the possible origin of the serotonin innervation of some parts of the brain. Moreover, comparing our results in birds with those obtained in other vertebrate species shows that the organization of the serotoninergic system in many regions of the avian brain is much like that found in reptiles and mammals. Springer-Verlag, 1996 Serotonin nationallicence Immunohistochemistry nationallicence Central nervous system nationallicence Pigeon nationallicence Ad : Archistriatum pars dorsalis nationallicence alp : area interpeduncularis nationallicence al : ansa lenticularis nationallicence Ann : nucleus annularis nationallicence APH : area parahippocampalis nationallicence Av : archistriatum pars ventralis nationallicence AVT : area ventralis (Tsai) nationallicence bcd : brachium conjunctivum descendens nationallicence BO : bulbus olfactorius nationallicence ca : commisssura anterior nationallicence CDL : area corticoidea dorsolateralis nationallicence Cer : cerebellum nationallicence cf : fiber layer of the olfactory bulb nationallicence cg : granular cell layer of the olfactory bulb nationallicence co : chiasma opticum nationallicence ct : commissura tectalis nationallicence dbc : decussatio brachiorum conjunctivorum nationallicence DL : nucleus dorsolateralis anterior thalami nationallicence DLP : nucleus dorsolateralis posterior thalami nationallicence DM : nucleus dorsomedialis thalami nationallicence dnt : decussatio nervi trochlearis nationallicence E : ectostriatum nationallicence Ec : ectopic area of the nucleus isthmo-opticus nationallicence EM : nucleus ectomamillaris nationallicence flm : fasciculus longitudinalis medialis nationallicence fpl : fasciculus prosencephali lateralis nationallicence FRL : formatio reticularis lateralis mesencephali nationallicence FRM : formatio reticularis medialis mesencephali nationallicence fu : fasciculus uncinatus nationallicence GCt : substantia grisea centralis nationallicence GLv : nucleus geniculatus lateralis pars ventralis nationallicence gr : granular cell layer of the cerebellum nationallicence HA : hyperstriatum accessorium nationallicence HD : hyperstriatum dorsale nationallicence HIS : hyperstriatum intercalatus superior nationallicence HL : nucleus habenularis lateralis nationallicence HM : nucleus habenularis medialis nationallicence Hp : hippocampus nationallicence HV : hyperstriatum ventrale nationallicence ICo : nucleus intercollicularis nationallicence i-flm : inter fasciculus longitudinalis medialis nationallicence Imc : nucleus ishmi pars magnocellularis nationallicence Ip : nucleus interpeduncularis nationallicence Ipc : nucleus isthmi pars parvocellularis nationallicence LA : nucleus lateralis anterior thalami nationallicence La : nucleus laminaris nationallicence LC : nucleus linearis caudalis nationallicence LHy : nucleus lateralis hypothalami nationallicence lm : lemniscus medialis nationallicence LoC : locus coeruleus nationallicence LPO : lobus paraolfactorius nationallicence ls : lemniscus spinalis nationallicence MLd : nucleus mesencephalicus lateralis pars dorsalis nationallicence mo : molecular layer of the cerebellum nationallicence MoV : nucleus motorius nervi trigemini nationallicence Mp : magnocellularis preopticus nationallicence N : neostriatum nationallicence NIII : nucleus nervi oculomotorii nationallicence nIII : nervus oculomotorius nationallicence NIV : nucleus nervi trochlearis nationallicence NV nucleus nervi trigemini : nV nervus trigeminus nationallicence NVII : nucleus nervifacialis nationallicence nVIII : nervus octavus nationallicence NIO : nucleus isthmo-opticus nationallicence om : tractus occipitomesencephalicus nationallicence OPH : hypothalamic periventricular organ nationallicence Os : nucleus olivaris superior nationallicence Ov : nucleus ovoidalis nationallicence PA : paleostriatum augmentatum nationallicence Po : nucleus pontis nationallicence POM : nucleus preoticus medialis nationallicence PP : paleostriatum primitivum nationallicence PrV : nucleus sensorius principalis nervi trigemini nationallicence PT : nucleus pretectalis nationallicence pu : Purkinje cell layer nationallicence qf : tractus quintofrontalis nationallicence Rai : nucleus raphe inferior nationallicence RasV : nucleus raphe superior pars ventralis nationallicence ReI : recessus infundibularis nationallicence Rm : nucleus reticularis magnocellularis nationallicence Rp : nucleus reticularis parvocellularis nationallicence RPc : nucleus reticularis pontis caudalis nationallicence RPO : nucleus reticularis pontis oralis nationallicence Rt : nucleus rotundus nationallicence Ru : nucleus ruber nationallicence S : septum nationallicence Sac : stratum album centrale nationallicence SCH : stratum cellulare hypothalami nationallicence Sgc : stratum griseum centrale nationallicence Sgf : stratum griseum et fibrosum superficiale nationallicence Sgfp : stratum griseum et fibrosum periventriculare nationallicence Sop : stratum opticum nationallicence SP : nucleus subpretectalis nationallicence SPC : nucleus superficialis parvocellularis nationallicence Spl : nucleus spiriformis lateralis nationallicence Spm : nucleus spiriformis medialis nationallicence SRt : nucleus subrotundus nationallicence SuC : nucleus subcoeruleus nationallicence to : tractus opticus nationallicence Tn : nucleus taeniae nationallicence TPc : nucleus tegmenti pedunculo-pontinus pars compacta nationallicence Tr : nucleus triangularis nationallicence tsm : tractus septomesencephalicus nationallicence ttd : nucleus et tractus descendens nervi trigemini nationallicence Tu : nucleus tuberis nationallicence Vel : nucleus vestibularis lateralis nationallicence Vem : nucleus vestibularis medialis nationallicence Vlt : nucleus ventrolateralis thalami nationallicence VT : nucleus ventrolateralis tegmenti nationallicence Zp-flm : zona perifasciculus longitudinalis medialis nationallicence Zp-NIII : zona perinervus oculomotorius nationallicence Challet E. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut Miceli D. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut Pierre J. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut Repérant J. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut Masicotte G. Department de Chimie-Biologie, Université du Québec, Trois-Rivières, Canada aut Herbin M. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut Vesselkin N. Institute Sechenov, Academy of Science of Russia, St. Petersburg, Russia aut Anatomy and Embryology Springer-Verlag 193/3(1996-03-01), 209-227 0340-2061 193:3<209 1996 193 429 https://doi.org/10.1007/BF00198325 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00198325 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Challet E. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut NATIONALLICENCE 700 1- Miceli D. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut NATIONALLICENCE 700 1- Pierre J. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut NATIONALLICENCE 700 1- Repérant J. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut NATIONALLICENCE 700 1- Masicotte G. Department de Chimie-Biologie, Université du Québec, Trois-Rivières, Canada aut NATIONALLICENCE 700 1- Herbin M. Laboratoire de Neuromorphologie, INSERM U 106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, 47 Boulevard de l'Hôpital, F-75651, 13, Paris Cedex, France aut NATIONALLICENCE 700 1- Vesselkin N. Institute Sechenov, Academy of Science of Russia, St. Petersburg, Russia aut NATIONALLICENCE 773 0- Anatomy and Embryology Springer-Verlag 193/3(1996-03-01), 209-227 0340-2061 193:3<209 1996 193 429 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer