caa a22 4500 477095410 CHVBK 20180405111526.0 cr unu---uuuuu 170330e19960401xx s 000 0 eng 10.1007/BF00186695 doi (NATIONALLICENCE)springer-10.1007/BF00186695 In situ hybridization for somatostatin mRNA in the adult rat: cingulate, insular, prepiriform, perirhinal, entorhinal, and retrosplenial cortical regions [Elektronische Daten] [B. Garrett, B. Finsen, A. Wree] The expression of somatostatin mRNA within the allocortex of the rat was examined by in situ hybridization with an alkaline phosphatase labeled probe. We sought to determine whether parcellation of the allocortex could be based upon the number and laminar location of the hybridized cells and to contrast the allocortical features with those of the isocortical areas. The cingulate region was characterized by intense, moderate, and faint cells, small to medium in size throughout the laminae. The retrosplenial region demonstrated a somewhat stratified appearance with an abundance of cells expressing somatostatin mRNA in the upper portion of the composite layer II-IV and also in the upper portion of layer VI. The insular region displayed more heterogeneity. The distribution of the cells hybridized for somatostatin mRNA formed distinctive configurations within the insular region (dorsal and ventral agranular insular areas) with no obvious generality. The perirhinal area resembled the ventral agranular insular area, and the cell distribution of the entorhinal and prepiriform areas displayed a common characteristic in that the primary axis of the perikarya of somatostatin mRNA expressing cells within the lower layers were oriented at almost every possible angle. The conclusion of the investigation is that in situ hybridization for somatostatin mRNA provides a means by which the areal boundaries within the allocortex may be drawn. Springer-Verlag, 1996 Neuropeptides nationallicence Limbic cortex nationallicence Allocortex nationallicence Mesocortex nationallicence Parcellation nationallicence Rat nationallicence Garrett B. Institute of Anatomy, Medical Faculty, University of Rostock, D-18055, Rostock, Germany aut Finsen B. Department of Anatomy and Cell Biology, Institute of Medical Biology, University of Odense, DK-5000, Odense C, Denmark aut Wree A. Institute of Anatomy, Medical Faculty, University of Rostock, D-18055, Rostock, Germany aut Anatomy and Embryology Springer-Verlag 193/4(1996-04-01), 387-395 0340-2061 193:4<387 1996 193 429 https://doi.org/10.1007/BF00186695 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00186695 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Garrett B. Institute of Anatomy, Medical Faculty, University of Rostock, D-18055, Rostock, Germany aut NATIONALLICENCE 700 1- Finsen B. Department of Anatomy and Cell Biology, Institute of Medical Biology, University of Odense, DK-5000, Odense C, Denmark aut NATIONALLICENCE 700 1- Wree A. Institute of Anatomy, Medical Faculty, University of Rostock, D-18055, Rostock, Germany aut NATIONALLICENCE 773 0- Anatomy and Embryology Springer-Verlag 193/4(1996-04-01), 387-395 0340-2061 193:4<387 1996 193 429 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer