caa a22 4500 477095526 CHVBK 20180405111526.0 cr unu---uuuuu 170330e19960501xx s 000 0 eng 10.1007/BF00185873 doi (NATIONALLICENCE)springer-10.1007/BF00185873 Spatial and temporal distribution of lamprin mRNA during chondrogenesis of trabecular cartilage in the sea lamprey [Elektronische Daten] [Kim McBurney, Fred Keeley, Frederick Kibenge, Glenda Wright] The temporal and spatial expression patterns of lamprin, the principle structural protein in lamprey cartilages, were examined by in situ hybridization during chondrogenesis of trabecular cartilage in day 17-33 post-fertilization prolarval lampreys. Lamprin mRNA transcripts were first detected during day 19, concomitant with the end of the condensation phase of chondrogenesis and the initiation of matrix synthesis as indicated by light microscopic examination. In the stages which followed, the hybridization signal increased with progressive intensity, paralleling matrix synthesis, suggesting transcriptional control of lamprin gene expression. Spatially, lamprin expression patterns mirrored the rostrocaudal development of the trabecular cartilage rudiment. No signal was detected over adjacent tissues or control sections. Some similarities exist between the temporal patterns of lamprin expression and the expression of matrix proteins such as elastin and collagen of higher vertebrates. It is concluded that certain aspects of chondrogenesis are critical to the normal development of a functional cartilaginous matrix and are conserved throughout the vertebrate taxa. Springer-Verlag, 1996 Cartilage nationallicence Matrix nationallicence Expression nationallicence In situ hybridization nationallicence Petromyzon nationallicence McBurney Kim Department of Anatomy and Physiology, Atlantic Veterinary College, University of Prince Edward Island, PEI, C1A 4P3, Charlottetown, Canada aut Keeley Fred Division of Cardiovascular Research, Research Institute, Hospital for Sick Children, M5G 1X8, Toronto, Ontario, Canada aut Kibenge Frederick Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, PEI, C1A 4P3, Charlottetown, Canada aut Wright Glenda Department of Anatomy and Physiology, Atlantic Veterinary College, University of Prince Edward Island, PEI, C1A 4P3, Charlottetown, Canada aut Anatomy and Embryology Springer-Verlag 193/5(1996-05-01), 419-426 0340-2061 193:5<419 1996 193 429 https://doi.org/10.1007/BF00185873 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00185873 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- McBurney Kim Department of Anatomy and Physiology, Atlantic Veterinary College, University of Prince Edward Island, PEI, C1A 4P3, Charlottetown, Canada aut NATIONALLICENCE 700 1- Keeley Fred Division of Cardiovascular Research, Research Institute, Hospital for Sick Children, M5G 1X8, Toronto, Ontario, Canada aut NATIONALLICENCE 700 1- Kibenge Frederick Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, PEI, C1A 4P3, Charlottetown, Canada aut NATIONALLICENCE 700 1- Wright Glenda Department of Anatomy and Physiology, Atlantic Veterinary College, University of Prince Edward Island, PEI, C1A 4P3, Charlottetown, Canada aut NATIONALLICENCE 773 0- Anatomy and Embryology Springer-Verlag 193/5(1996-05-01), 419-426 0340-2061 193:5<419 1996 193 429 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer