caa a22 4500 477095577 CHVBK 20180405111526.0 cr unu---uuuuu 170330e19960501xx s 000 0 eng 10.1007/BF00185878 doi (NATIONALLICENCE)springer-10.1007/BF00185878 Dorsal root ganglion neuron development in chick and rat [Elektronische Daten] [Seiji Matsuda, Peter Baluk, Daisaburo Shimizu, Takashi Fujiwara] The aim of this study was to compare the morphological development of dorsal root ganglion neurons in embryonic and early postnatal chicks and rats. The three-dimensional architecture of neurons was observed in ganglia in situ and in dissociated neurons by scanning electron microscopy after removal of the capsule and connective tissue. The percentages of neurons at different developmental stages were determined. The general morphological changes in the chick resembled those in the rat but the timing was different. In both chick and rat, the majority of neurons were bipolar at early stages of development (embryonic day 6 in chick and day 14 in rats) and later underwent pseudo-unipolarization to become mostly unipolar neurons at hatching or birth. This maturation event started at an earlier stage in chick embryos than in rats, with 57% unipolar neurons in chick and only 7% in rat on embryonic day 14. However, just after hatching or birth, at day 22 of development, a larger proportion of immature unipolar neurons remained in chicks (13%) than in rats (3%). We conclude that these differences should be taken into consideration in designing experiments on dorsal root ganglion neurons grown in tissue culture. Springer-Verlag, 1996 Spinal ganglia nationallicence Sensory ganglia nationallicence Pseudo-unipolarization nationallicence Scanning electron microscopy nationallicence Differentiation nationallicence Matsuda Seiji Department of Anatomy, Ehime University School of Medicine, Shigenobu, 791-02, Ehime, Japan aut Baluk Peter Cardiovascular Research Institute, School of Medicine, 94143-0131, San Francisco, CA, USA aut Shimizu Daisaburo Central Research Laboratory, Ehime University School of Medicine, Shigenobu, Ehime, Japan aut Fujiwara Takashi Laboratory Animal Center, Ehime University School of Medicine, Shigenobu, Ehime, Japan aut Anatomy and Embryology Springer-Verlag 193/5(1996-05-01), 475-480 0340-2061 193:5<475 1996 193 429 https://doi.org/10.1007/BF00185878 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00185878 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Matsuda Seiji Department of Anatomy, Ehime University School of Medicine, Shigenobu, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Baluk Peter Cardiovascular Research Institute, School of Medicine, 94143-0131, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Shimizu Daisaburo Central Research Laboratory, Ehime University School of Medicine, Shigenobu, Ehime, Japan aut NATIONALLICENCE 700 1- Fujiwara Takashi Laboratory Animal Center, Ehime University School of Medicine, Shigenobu, Ehime, Japan aut NATIONALLICENCE 773 0- Anatomy and Embryology Springer-Verlag 193/5(1996-05-01), 475-480 0340-2061 193:5<475 1996 193 429 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer