caa a22 4500 477105149 CHVBK 20180405111551.0 cr unu---uuuuu 170330e19960901xx s 000 0 eng 10.1007/BF01574688 doi (NATIONALLICENCE)springer-10.1007/BF01574688 The ecology and evolution of bacteriocins [Elektronische Daten] [M Riley, D Gordon] In this review we focus on the ecological and evolutionary forces that determine the frequency and diversity of colicins inEscherichia coli. To begin, we describe that this killing phenotype is ubiquitous inE. coli, with as many as 50% of the isolates from a population producing colicin toxins, and that each population sampled has its own unique distribution of the more than 20 known colicin types. Next, we explore the dynamics of colicinogeny, which exhibits a typical form of frequency dependence, where the likelihood of successful colicin invasion into a population increases as the initial density of colicinogenic cells increases. We then incorporate thoughts on the evolution of chromosomal resistance to colicins and describe how resistance might influence the dynamics of colicinogen invasion and maintenance and the resulting colicin diversity. The final section deals with a genetic and phylogenetic characterization of colicins and a discussion of the evolutionary mechanisms responsible for generating colicin diversity. In this final section we provide details of the different molecular mechanisms known to play a role in generating colicin diversity, including the two most dominant forces in colincin evolution: recombination and positive, deversifying, selection. Society for Industrial Microbiology, 1996 bacteriocins nationallicence colicins nationallicence evolution nationallicence ecology nationallicence Escherichia coli nationallicence Riley M. Department of Biology, Osborn Memorial Laboratories, Yale University, PO Box 6666, 06511-7444, New Haven, Connecticut, USA aut Gordon D. Division of Botany and Zoology, Australian National University, 0200, Canberra, ACT, Australia aut Journal of Industrial Microbiology Springer-Verlag 17/3-4(1996-09-01), 151-158 0169-4146 17:3-4<151 1996 17 10295 https://doi.org/10.1007/BF01574688 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01574688 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Riley M. Department of Biology, Osborn Memorial Laboratories, Yale University, PO Box 6666, 06511-7444, New Haven, Connecticut, USA aut NATIONALLICENCE 700 1- Gordon D. Division of Botany and Zoology, Australian National University, 0200, Canberra, ACT, Australia aut NATIONALLICENCE 773 0- Journal of Industrial Microbiology Springer-Verlag 17/3-4(1996-09-01), 151-158 0169-4146 17:3-4<151 1996 17 10295 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer