caa a22 4500 477105629 CHVBK 20180405111552.0 cr unu---uuuuu 170330e19960801xx s 000 0 eng 10.1007/BF01570051 doi (NATIONALLICENCE)springer-10.1007/BF01570051 Response surface optimization for the continuous glucose isomerization process [Elektronische Daten] [W Bazaraa, E Hassan] Production of fructose via a continuous glucose isomerization process was optimized using response surface methodology. Glucose isomerization was performed using immobilized glucose isomerase in a flow-through tubular reactor. Process factors eg pH (7.0-7.8), temperature (50-60°C), flow rate (5-17 ml min−1) and glucose content (30-50% w/w) of the feedstock solution were simultaneously tested according to a central composite experimental design. Measured responses such as % isomerization, and fructose yield (gh−1) has an excellent correlation with tested factors. The highest desirability,D, (geometric mean of % isomerization and fructose yield) was obtained when the feedstock (56-60°C) had 34-36% glucose, a pH of 7.4-7.8 and was pumped at 15 ml min−1. Society for Industrial Microbiology, 1996 immobilized glucose isomerase nationallicence response surface methodology nationallicence optimization nationallicence Bazaraa W. Department of Food Science and Technology, College of Agriculture, Cairo University, Giza, Egypt aut Hassan E. Amriya Pharmaceutical Industries, Alexandria, Egypt aut Journal of Industrial Microbiology Springer-Verlag 17/2(1996-08-01), 100-103 0169-4146 17:2<100 1996 17 10295 https://doi.org/10.1007/BF01570051 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01570051 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bazaraa W. Department of Food Science and Technology, College of Agriculture, Cairo University, Giza, Egypt aut NATIONALLICENCE 700 1- Hassan E. Amriya Pharmaceutical Industries, Alexandria, Egypt aut NATIONALLICENCE 773 0- Journal of Industrial Microbiology Springer-Verlag 17/2(1996-08-01), 100-103 0169-4146 17:2<100 1996 17 10295 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer