caa a22 4500 477106749 CHVBK 20180405111555.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF01411475 doi (NATIONALLICENCE)springer-10.1007/BF01411475 Anterior callosotomy in the management of intractable epileptic seizures: Significance of the extent of resection [Elektronische Daten] [D. Sakas, J. Phillips] Summary: We report our series of twenty consecutive patients who underwent corpus callosotomy for medically intractable epilepsy. The follow-up is 6.7±0.5 years. Sixteen of 20 patients (80%) had a favourable outcome. Six patients have remained free of major generalized motor seizures, and ten further patients experienced significant sustained reduction in the severity and frequency of the seizures. The type of seizures associated with improved outcome were drop attacks, and generalized tonic-clonic seizures, in 11 of 13 (85%) and 14 of 18 (78%) of the patients, respectively. In order to establish the extent of necessary callosal resection to achieve seizure control, the outcome of patients was correlated with the extent of callosal sectioning on postoperative magnetic resonance imaging. This study confirms that an anterior callosal resection of two-thirds (or 65%) is sufficient to achieve significant improvement in seizure control with an acceptable morbidity in judiciously selected patients with medically intractable epilepsy. Results also suggest that the patient's history and clinical classification of the seizures have prognostic value as selection criteria for patients referred for this operation. In this series, no prognostic value was established for pre-operative electroencephalographic patterns, or neuroimaging findings. Springer-Verlag, 1996 Epilepsy nationallicence corpus callosum nationallicence drop attacks nationallicence Sakas D. National Centre for Neurosurgery and Richmond Institute of Neurological Sciences, Beaumont Hospital, Dublin, Ireland aut Phillips J. National Centre for Neurosurgery and Richmond Institute of Neurological Sciences, Beaumont Hospital, Dublin, Ireland aut Acta Neurochirurgica Springer-Verlag 138/6(1996-06-01), 700-707 0001-6268 138:6<700 1996 138 701 https://doi.org/10.1007/BF01411475 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01411475 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sakas D. National Centre for Neurosurgery and Richmond Institute of Neurological Sciences, Beaumont Hospital, Dublin, Ireland aut NATIONALLICENCE 700 1- Phillips J. National Centre for Neurosurgery and Richmond Institute of Neurological Sciences, Beaumont Hospital, Dublin, Ireland aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer-Verlag 138/6(1996-06-01), 700-707 0001-6268 138:6<700 1996 138 701 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer