caa a22 4500 477106773 CHVBK 20180405111555.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF01411484 doi (NATIONALLICENCE)springer-10.1007/BF01411484 Gangliosides modulate the growth rate and cell phenotype of a murine primitive neuro-ectodermal tumour [Elektronische Daten] [J. Vaquero, M. Zurita, S. Oya, S. Coca] Summary: Intratumoural administration of gangliosides (GSD) into a murine primitive neuro-ectodermal tumour, growing in the epicranial subcutaneous tissue of syngenic rats, results in a decrease in the tumour growth rate and causes a more differentiated phenotype of tumour cell, with immunohistochemical expression of neuronal markers. These findings suggest that the potential usefulness of intralesional administration of GSD for the control of tumours of primitive neuro-epithelial character could be considered. Springer-Verlag, 1996 ENU-induced neoplasms nationallicence experimental brain tumours nationallicence primitive neuro-ectodermal tumours, gangliosides nationallicence biological response modifiers nationallicence Vaquero J. Laboratory of Neuro-oncology, Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Spain aut Zurita M. Laboratory of Neuro-oncology, Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Spain aut Oya S. Laboratory of Neuro-oncology, Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Spain aut Coca S. Laboratory of Neuro-oncology, Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Spain aut Acta Neurochirurgica Springer-Verlag 138/6(1996-06-01), 759-762 0001-6268 138:6<759 1996 138 701 https://doi.org/10.1007/BF01411484 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01411484 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vaquero J. Laboratory of Neuro-oncology, Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Spain aut NATIONALLICENCE 700 1- Zurita M. Laboratory of Neuro-oncology, Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Spain aut NATIONALLICENCE 700 1- Oya S. Laboratory of Neuro-oncology, Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Spain aut NATIONALLICENCE 700 1- Coca S. Laboratory of Neuro-oncology, Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Spain aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer-Verlag 138/6(1996-06-01), 759-762 0001-6268 138:6<759 1996 138 701 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer