caa a22 4500 477107702 CHVBK 20180405111559.0 cr unu---uuuuu 170330e19961001xx s 000 0 eng 10.1007/BF01809746 doi (NATIONALLICENCE)springer-10.1007/BF01809746 Does nimodipine influence sex difference in outcome after aneurysmal subarachnoid haemorrhage? [Elektronische Daten] [J. Hauerberg, J. Rosenørn, E. Skriver] Summary: Before nimodipine was introduced as a standard treatment in patients with aneurysmal subarachnoid haemorrhage (SAH) females had a significantly poorer outcome which might be due to a higher frequency of delayed cerebral ischaemia (DCI). We evaluated the overall outcome with regard to gender in 188 consecutive patients with a verified ruptured intracranial aneurysm treated with nimodipine. The only significant differences concerning prognostic factors between the sexes were a higher frequency of SAH at the primary CT in females (p<0.05) and a higher frequency of middle cerebral artery aneurysms in females (p<0.01). These factors affect the outcome in females unfavourably. However, contrary to previous studies, we found no difference in overall outcome after three months between the sexes in this clinical material. Our observation can be explained by a positive effect of nimodipine on DCI. Springer-Verlag, 1996 Delayed cerebral ischaemia nationallicence intracranial aneurysm nationallicence nimodipine nationallicence gender nationallicence subarachnoid haemorrhage nationallicence Hauerberg J. University Clinic of Neurosurgery, Copenhagen County Hospital, Glostrup, Denmark aut Rosenørn J. University Clinic of Neurosurgery, Copenhagen County Hospital, Glostrup, Denmark aut Skriver E. University Clinic of Radiology, Copenhagen County Hospital, Glostrup, Denmark aut Acta Neurochirurgica Springer-Verlag 138/10(1996-10-01), 1168-1171 0001-6268 138:10<1168 1996 138 701 https://doi.org/10.1007/BF01809746 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01809746 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hauerberg J. University Clinic of Neurosurgery, Copenhagen County Hospital, Glostrup, Denmark aut NATIONALLICENCE 700 1- Rosenørn J. University Clinic of Neurosurgery, Copenhagen County Hospital, Glostrup, Denmark aut NATIONALLICENCE 700 1- Skriver E. University Clinic of Radiology, Copenhagen County Hospital, Glostrup, Denmark aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer-Verlag 138/10(1996-10-01), 1168-1171 0001-6268 138:10<1168 1996 138 701 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer