caa a22 4500 477107729 CHVBK 20180405111600.0 cr unu---uuuuu 170330e19961001xx s 000 0 eng 10.1007/BF01809747 doi (NATIONALLICENCE)springer-10.1007/BF01809747 Metastasis in meningioma [Elektronische Daten] [S. Ather Enam, S. Abdulrauf, B. Mehta, G. Malik, A. Mahmood] Summary: Meningioma is a neoplastic growth originating from the leptomeninges. Although meningiomas are usually benign, malignant meningiomas with distant metastases occur infrequently. There is little precise information in the literature regarding the frequency of metastases in meningiomas; their incidence has been vaguely reported to be less than 1 per 1,000. Furthermore, most of the previous studies have also included haemangiopericytomas which most recent authorities do not consider meningiomas. In our experience with the management of 396 meningiomas over the past 18 years, 7 meningiomas were classified as malignant by defined histological criteria. After initially presenting as solitary intracranial neoplasms, three of the malignant meningiomas metastasized to extracranial tissues. Collectively, the metastases involved the vertebral bodies, liver, pelvis, long bones, and the spinal cord. This confers an incidence of metastasis of 0.76% when considering all the meningiomas, and an incidence of approximately 43% when considering only malignant meningioma; both percentages are significantly higher than reported previously. This high incidence of metastasis in the malignant meningioma indicates a worse prognosis than formerly assessed and also characterizes the malignant meningioma as a primary central nervous system neoplasm with one of the highest rates of metastasis. In addition, when malignant meningioma is classified by following strict criteria, the risk of metastasis in the ensuing clinical course can be predicted with a higher reliability. Springer-Verlag, 1996 Meningioma nationallicence metastasis nationallicence malignant nationallicence Ather Enam S. Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA aut Abdulrauf S. Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA aut Mehta B. Department of Diagnostic Radiology, Henry Ford Hospital, Detroit, Michigan, USA aut Malik G. Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA aut Mahmood A. Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA aut Acta Neurochirurgica Springer-Verlag 138/10(1996-10-01), 1172-1178 0001-6268 138:10<1172 1996 138 701 https://doi.org/10.1007/BF01809747 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01809747 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ather Enam S. Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA aut NATIONALLICENCE 700 1- Abdulrauf S. Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA aut NATIONALLICENCE 700 1- Mehta B. Department of Diagnostic Radiology, Henry Ford Hospital, Detroit, Michigan, USA aut NATIONALLICENCE 700 1- Malik G. Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA aut NATIONALLICENCE 700 1- Mahmood A. Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer-Verlag 138/10(1996-10-01), 1172-1178 0001-6268 138:10<1172 1996 138 701 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer