caa a22 4500 477108148 CHVBK 20180405111601.0 cr unu---uuuuu 170330e19960801xx s 000 0 eng 10.1007/BF01411292 doi (NATIONALLICENCE)springer-10.1007/BF01411292 Micro-invasive squamous cell carcinoma arising in a pre-existing intraventricular epidermoid cyst [Elektronische Daten] Case report and literature review [C. Bayindir, N. Balak, A. Karasu] Summary: The authors report the case of a 67-year-old woman with primary micro-invasive squamous cell carcinoma located in the lateral ventricle and originating from an epidermoid cyst. Radiological and histological features of the neoplasm are described and the relevant literature is studied briefly. Two consecutive surgical specimens were studied by light microscopy. In the histological sections of the subtotally removed material of the first operation, the cyst wall was layered by epithelium — the same as expected in an epidermoid cyst — and showed foci with mild to moderate dysplastic changes. Theses changes did not reach up to the degree of a carcinoma. However, because the cyst could not be resected totally, the possibility of a squamous cell carcinoma was considered in the differential diagnosis. In the present case, the diagnosis was firmly established in a second surgical specimen obtained ten months after the first operation. Now, the tumour proved to be a primary squamous cell carcinoma, which exhibited severe dysplastic changes. Primary squamous cell carcinoma of brain is extremely rare. To our knowledge, only 20 such tumours with pre-existing epidermoid cyst have been reported in the central nervous system. The intriguing observation in this case is a three year recurrence free survival following the subtotal removal of the malignant neoplasm at the second surgery, without postoperative radiotherapy. Springer-Verlag, 1996 Squamous cell carcinoma nationallicence brain neoplasm nationallicence epidermoid cyst nationallicence malignant transformation nationallicence Bayindir C. Division of Neuropathology, University of Istanbul, Istanbul Faculty of Medicine, Istanbul aut Balak N. Department of Neurosurgery, Bakirköy State Hospital, Istanbul aut Karasu A. Department of Neurosurgery, University of Istanbul, Istanbul Faculty of Medicine, Istanbul, Turkey aut Acta Neurochirurgica Springer-Verlag 138/8(1996-08-01), 1008-1012 0001-6268 138:8<1008 1996 138 701 https://doi.org/10.1007/BF01411292 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01411292 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bayindir C. Division of Neuropathology, University of Istanbul, Istanbul Faculty of Medicine, Istanbul aut NATIONALLICENCE 700 1- Balak N. Department of Neurosurgery, Bakirköy State Hospital, Istanbul aut NATIONALLICENCE 700 1- Karasu A. Department of Neurosurgery, University of Istanbul, Istanbul Faculty of Medicine, Istanbul, Turkey aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer-Verlag 138/8(1996-08-01), 1008-1012 0001-6268 138:8<1008 1996 138 701 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer