caa a22 4500 477108474 CHVBK 20180405111602.0 cr unu---uuuuu 170330e19960201xx s 000 0 eng 10.1007/BF01411355 doi (NATIONALLICENCE)springer-10.1007/BF01411355 Effect of CO2 laser on spinal epidural fibrosis [Elektronische Daten] [A. Colak, M. Bavbek, N. Aydin, N. Renda, B. Acikgöz] Summary: In this study the effect of CO2 laser on spinal epidural fibrosis was examined in 24 guinea pigs which were divided into two groups. The first group was the control group, the second one the CO2 laser group. All animals had laminectomies at 3 levels. Re-exploration was performed three months after the laminectomy. In the second group the same procedure was performed but at the end of the re-exploration, CO2 laser irradiation of the epidural fibrotic tissue was done. The wounds in both groups were closed again. Four months later all animals were sacrificed, for verification and quantification of scar formation (postoperative fibrosis) light microscopic examinations and determination of hydroxyproline were done, using Bergman's spectrophotometric method. The differences which were observed between the two groups were statistically significant (U ∶ 134, p < 0.05). This study demonstrates the reducing effect of CO2 laser irradiation on epidural scar formation. The findings encourage its use as an alternative method of prevention of epidural fibrosis after spinal surgery. Springer-Verlag, 1996 CO2 laser nationallicence epidural fibrosis nationallicence postlaminectomy scar nationallicence 5-hydroxyproline nationallicence Colak A. Departments of Neurosurgery and Pathology, Inönü University, Malatya aut Bavbek M. Departments of Neurosurgery, Social Security Hospital, Ankara aut Aydin N. Departments of Neurosurgery and Pathology, Inönü University, Malatya aut Renda N. Departments of Biochemistry, Hacettepe University, Anakara, Turkey aut Acikgöz B. Departments of Neurosurgery, Baymdir Hospital, Ankara aut Acta Neurochirurgica Springer-Verlag 138/2(1996-02-01), 162-166 0001-6268 138:2<162 1996 138 701 https://doi.org/10.1007/BF01411355 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01411355 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Colak A. Departments of Neurosurgery and Pathology, Inönü University, Malatya aut NATIONALLICENCE 700 1- Bavbek M. Departments of Neurosurgery, Social Security Hospital, Ankara aut NATIONALLICENCE 700 1- Aydin N. Departments of Neurosurgery and Pathology, Inönü University, Malatya aut NATIONALLICENCE 700 1- Renda N. Departments of Biochemistry, Hacettepe University, Anakara, Turkey aut NATIONALLICENCE 700 1- Acikgöz B. Departments of Neurosurgery, Baymdir Hospital, Ankara aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer-Verlag 138/2(1996-02-01), 162-166 0001-6268 138:2<162 1996 138 701 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer