caa a22 4500 477108547 CHVBK 20180405111602.0 cr unu---uuuuu 170330e19960201xx s 000 0 eng 10.1007/BF01411360 doi (NATIONALLICENCE)springer-10.1007/BF01411360 Temperature regulation as possible prognostic indicator in patients with acute intracranial lesions [Elektronische Daten] [R. Behr, D. Ehrlinspiel, P. Christophis] Summary: 24 patients, 16 after severe head injury and 8 after spontaneous intracranial haematoma, were investigated by external cold load in order to determine their thermoregulatory capabilities. Tympanic temperature, several skin temperatures and oxygen consumption were measured. The patients where examined for SSEP and AEP. The cold induced thermoregulatory threshold temperature was determined by calculating the mean body temperature and by determining mean body temperature at which oxygen consumption increased due to the external cold load. In all patients core temperature and mean body temperature were significantly elevated by 1 °C compared to controls. There was no difference of the course of the various body temperatures during cold load in the patient groups. In the trauma group 8 patients were able to increase oxygen use (VO2) during cold exposure, the other 8 patients showed no physiological thermoregulatory reaction. The heatproduction threshold temperature was increased by 1 °C in the patient groups compared to controls. There was no significant correlation of AEP and SSEP findings to a preserved or disturbed thermoregulatory reaction. In the trauma patients, who were able to respond to a cold load, the outcome was significantly better (GOS=3-5), than in those patients, who did not show a physiological increase of VO2 due to the cold load (GOS=1-2). In conclusion, measurement of body temperatures alone is not sufficient to determine termoregulatory capacities. An examination using thermophysiological methods however provides more information about the function and structure damaged after severe head injury. An intact thermoregulatory systems seems to be correlated with a better prognosis after head injury. Springer-Verlag, 1996 Head injury nationallicence temperature regulation nationallicence prognostic implications nationallicence shift of thermoregulatory threshold temperatures nationallicence Behr R. Department of Neurosurgery, University of Würzburg, Federal Republic of Germany aut Ehrlinspiel D. Department of Neurosurgery, University of Giessen, Federal Republic of Germany aut Christophis P. Department of Neurosurgery, University of Giessen, Federal Republic of Germany aut Acta Neurochirurgica Springer-Verlag 138/2(1996-02-01), 192-199 0001-6268 138:2<192 1996 138 701 https://doi.org/10.1007/BF01411360 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01411360 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Behr R. Department of Neurosurgery, University of Würzburg, Federal Republic of Germany aut NATIONALLICENCE 700 1- Ehrlinspiel D. Department of Neurosurgery, University of Giessen, Federal Republic of Germany aut NATIONALLICENCE 700 1- Christophis P. Department of Neurosurgery, University of Giessen, Federal Republic of Germany aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer-Verlag 138/2(1996-02-01), 192-199 0001-6268 138:2<192 1996 138 701 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer