caa a22 4500 477108733 CHVBK 20180405111603.0 cr unu---uuuuu 170330e19961101xx s 000 0 eng 10.1007/BF01411053 doi (NATIONALLICENCE)springer-10.1007/BF01411053 Primary spinal column sarcomas [Elektronische Daten] [E. Tasdemiroglu, E. Bagatur, I. Ayan, E. Darendeliler, R. Patchell] Summary: Five cases of primary spinal column sarcomas are presented. Sarcomas primarily originating from paravertebral soft tissues were excluded. Patients' age ranged from 1 to 14 years (mean 8.4 years). The male: female ratio was 2∶3. Two patients had Ewing's sarcoma (ES) originating from L5-S1 and L4-5 pedicles, respectively; two patients had mesenchymal chondrosarcoma (MCS) originating from L1-2 pedicles and L5 body, respectively; and one patient had osteogenic sarcoma (OS) of C4 body. All patients clinically presented with pain and progressive weakness of the extremities. The time that elapsed between the onset of symptoms and diagnoses ranged from one to five months. All cases were treated with chemotherapy, radiotherapy and subtotal tumour resection with spinal canal decompression. Two cases received posterior spinal fusion operations. Three patients were alive 10 to 98 months following diagnosis. Only the case with ES of L5-S1 pedicles was in complete remission and off therapy at the 98th postoperative month. The two MCS cases were in partial remission, and were receiving chemoterapy at the time of analysis. These tumours caused similar clinical findings and prognoses, and required combined treatment, which consisted of surgery, radiotherapy and chemotherapy; histologically three different types of malignant tumours are presented in the same category. We preferred surgical decompression and stabilization procedures especially for neurologically symptomatic patients, even if they had extensive tumours with high grades. By spinal canal decompression and stabilisation, we did not intend to cure the disease; however, we intended to provide neurological improvement, spinal stabilisation, improved quality of life, early mobilisation of the patient, and cytoreduction by means of surgical tumour ablation, which could render the chemotherapy more effective. Springer-Verlag, 1996 Children nationallicence Ewing's sarcoma nationallicence mesenchymal chondrosarcoma nationallicence osteosarcoma nationallicence chemotheapy nationallicence spinal fusion nationallicence Tasdemiroglu E. Incirli Hospital, Neurosurgery Service, Istanbul, Turkey aut Bagatur E. Incirli Hospital, Orthopaedic Surgery Service, Istanbul, Turkey aut Ayan I. Department of Paediatric Oncology, University of Istanbul, Institute of Oncology, Istanbul, Turkey aut Darendeliler E. Department of Radiation Oncology, University of Istanbul, Institute of Oncology, Istanbul, Turkey aut Patchell R. Division of Neurosurgery, University of Kentucky Medical Center, Lexington, KY, USA aut Acta Neurochirurgica Springer-Verlag 138/11(1996-11-01), 1261-1266 0001-6268 138:11<1261 1996 138 701 https://doi.org/10.1007/BF01411053 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01411053 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tasdemiroglu E. Incirli Hospital, Neurosurgery Service, Istanbul, Turkey aut NATIONALLICENCE 700 1- Bagatur E. Incirli Hospital, Orthopaedic Surgery Service, Istanbul, Turkey aut NATIONALLICENCE 700 1- Ayan I. Department of Paediatric Oncology, University of Istanbul, Institute of Oncology, Istanbul, Turkey aut NATIONALLICENCE 700 1- Darendeliler E. Department of Radiation Oncology, University of Istanbul, Institute of Oncology, Istanbul, Turkey aut NATIONALLICENCE 700 1- Patchell R. Division of Neurosurgery, University of Kentucky Medical Center, Lexington, KY, USA aut NATIONALLICENCE 773 0- Acta Neurochirurgica Springer-Verlag 138/11(1996-11-01), 1261-1266 0001-6268 138:11<1261 1996 138 701 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer