caa a22 4500 477112722 CHVBK 20180405111614.0 cr unu---uuuuu 170330e19960501xx s 000 0 eng 10.1007/BF01745173 doi (NATIONALLICENCE)springer-10.1007/BF01745173 Wall composition in intravascular ultrasound layered appearance of human coronary artery [Elektronische Daten] [Shigeo Kawano, Masakazu Yamagishi, Hiroyuki Hao, Chikao Yutani, Kunio Miyatake] Summary: To evaluate the impact of histological factors on the appearance of the wall of the coronary artery by intravascular ultrasound (IVUS), we performed an in vitro study of 34 coronary artery segments from eight autopsied patients. We assumed the coronary cross section to be divided into four equal parts, and assessed the quadrants with maximal and minimal wall thickness by IVUS (30MHz; 4.3Fr; 1 800rpm) and by a histological study. The histological layer thickness and composition were also evaluated in terms of their contribution to the appearance of the ultrasound layer. Fifty-eight quadrants were clearly visible on ultrasound. A threelayered appearance, with inner echogenic, subjacent sonolucent, and outer echogenic layers, was observed in 32 quadrants, while 26 quadrants showed a two-layered appearance, with inner and outer echogenic layers. The thickness of the inner echogenic layer (0.77 ± 0.38mm) was moderately correlated with the intimal thickness (0.51 ± 0.45mm;r = 0.85, standard error of estimate [SEE] = 0.24 mm); however, the correlation was significantly improved when the thickness of the inner echogenic plus sonolucent layers (0.89 ± 0.47mm) was compared with that of the intima plus media (0.69 ± 0.47 mm;r = 0.94, SEE = 0.15 mm;P = 0.012 between the coefficients). Discriminant analysis showed that intimal hyalinization, associated with intimal thickening, was strongly related to the presence of the three-layered appearance on IVUS (F to enter 40.0,P < 0.0001). These results indicate that the ultrasound layered appearance of human coronary arteries varies with histological alterations. We suggest that the thickness of the inner echogenic plus sonolucent layers on IVUS represents the intimal plus medial thickness observed by histology, and that the use of this value may be appropriate in the assessment of coronary wall thickening associated with atherosclerosis. Springer-Verlag, 1996 Intravascular ultrasound nationallicence Coronary atherosclerosis nationallicence Layered appearance nationallicence Kawano Shigeo Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, 565, Osaka, Japan aut Yamagishi Masakazu Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, 565, Osaka, Japan aut Hao Hiroyuki Division of Pathology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, 565, Suita, Osaka, Japan aut Yutani Chikao Division of Pathology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, 565, Suita, Osaka, Japan aut Miyatake Kunio Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, 565, Osaka, Japan aut Heart and Vessels Springer-Verlag 11/3(1996-05-01), 152-159 0910-8327 11:3<152 1996 11 380 https://doi.org/10.1007/BF01745173 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01745173 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kawano Shigeo Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, 565, Osaka, Japan aut NATIONALLICENCE 700 1- Yamagishi Masakazu Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, 565, Osaka, Japan aut NATIONALLICENCE 700 1- Hao Hiroyuki Division of Pathology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, 565, Suita, Osaka, Japan aut NATIONALLICENCE 700 1- Yutani Chikao Division of Pathology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, 565, Suita, Osaka, Japan aut NATIONALLICENCE 700 1- Miyatake Kunio Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, 565, Osaka, Japan aut NATIONALLICENCE 773 0- Heart and Vessels Springer-Verlag 11/3(1996-05-01), 152-159 0910-8327 11:3<152 1996 11 380 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer