caa a22 4500 477112781 CHVBK 20180405111614.0 cr unu---uuuuu 170330e19960501xx s 000 0 eng 10.1007/BF01745174 doi (NATIONALLICENCE)springer-10.1007/BF01745174 Coronary flow reserve and exercise capacity in hypertrophic cardiomyopathy [Elektronische Daten] [Paweł Dimitrow, Marek Krzanowski, Wojciech Bodzoń, Andrzej Szczeklik, Jacek Dubiel] Summary: The aim of this study was to evaluate the relation of coronary flow velocity (CFV) and coronary flow reserve (CFR) to exercise capacity in ten verapamil-treated patients with hypertrophic cardiomyopathy (HC). Using Doppler transesophageal echocardiography, we assessed diastolic CFV in the proximal left anterior descending coronary artery at baseline and after administering 0.56 mg/kg intravenous dipyridamole. The CFR was calculated as the postdipyridamole/baseline diastolic CFV ratio. A maximal symptom-limited exercise treadmill test was performed according to a modified Bruce protocol and the exercise capacity was expressed as metabolic equivalents. The mean value for baseline diastolic CFV was 59 ± 27cm/s; this increased after dipyridamole to 134 ± 57cm/s. The CFR was 2.37 ± 0.67. Baseline diastolic CFV correlated negatively with both exercise duration (r = −0.69;P < 0.05) and value for metabolic equivalents (r = −0.70;P < 0.05). CFR was weakly and non-significantly related to exercise duration (r = 0.40;P > 0.05) and to the value for metabolic equivalents (r = 0.32;P > 0.05). Shortening of exercise time and decreasing metabolic equivalents were correlated with increased baseline diastolic CFV. Dipyridamole-assessed CFR, was weakly related to parameters of exercise capacity. Springer-Verlag, 1996 Hypertrophic cardiomyopathy nationallicence Exercise tolerance nationallicence Coronary flow reserve nationallicence Dimitrow Paweł Second Department of Cardiology, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut Krzanowski Marek Second Chair of Internal Medicine, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut Bodzoń Wojciech Second Chair of Internal Medicine, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut Szczeklik Andrzej Second Chair of Internal Medicine, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut Dubiel Jacek Second Department of Cardiology, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut Heart and Vessels Springer-Verlag 11/3(1996-05-01), 160-164 0910-8327 11:3<160 1996 11 380 https://doi.org/10.1007/BF01745174 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01745174 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dimitrow Paweł Second Department of Cardiology, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut NATIONALLICENCE 700 1- Krzanowski Marek Second Chair of Internal Medicine, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut NATIONALLICENCE 700 1- Bodzoń Wojciech Second Chair of Internal Medicine, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut NATIONALLICENCE 700 1- Szczeklik Andrzej Second Chair of Internal Medicine, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut NATIONALLICENCE 700 1- Dubiel Jacek Second Department of Cardiology, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501, Kraków, Poland aut NATIONALLICENCE 773 0- Heart and Vessels Springer-Verlag 11/3(1996-05-01), 160-164 0910-8327 11:3<160 1996 11 380 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer