caa a22 4500 477112994 CHVBK 20180405111615.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF01744508 doi (NATIONALLICENCE)springer-10.1007/BF01744508 Acute changes in left ventricular function after percutaneous transluminal mitral valvuloplasty [Elektronische Daten] [Renato Razzolini, Angelo Ramondo, Giambattista Isabella, Paolo Cardaioli, Francesco Campisi, Alessandro De Leo, Raffaello Chioin] Summary: Percutaneous balloon mitral valvuloplasty (PBMV) has been shown to induce an immediate increase in the left ventricular end-diastolic volume, which increase, in turn, has been attributed to an increase in left ventricular compliance. We studied 51 patients, 41 women and 10 men, who underwent PBMV, and were in sinus rhythm before and after the procedure. Heart rate did not vary significantly. There were increases in left ventricular end-diastolic volume (97.5 ± 25.6 vs 112.7 ± 25.7ml/m2,P < 0.001), left ventricular end-diastolic pressure (8.7 ± 3.0 vs 9.7 ± 4.3mmHg,P = 0.04), and both left ventricular systolic pressure and stress (118 ± 20.5 vs 123 ± 23.2mmHg and 468 ± 129 vs 580 ± 164mmHg;P = 0.04 andP < 0.001, respectively). The elastic stiffness constant did not vary (16.2 ± 1.9 vs 15.7 ± 1.9 (dimensionless units),P = 0.2). The increase in volume seemed to be particularly important when the ventricle appeared to be "shrunken” before PBMV. This increase was still present after a 1 year follow up. Thus, PBMV determines an increase in both end-diastolic volume and pressure, so that the left ventricle appears to move along a single pressurevolume curve. This enlargement evokes the Frank Starling mechanism, and improves systolic performance. Since it is still evident after a 1 year follow up, some concern may arise when a simultaneous volume overload is present, as in aortic insufficiency. Springer-Verlag, 1996 Percutaneous balloon mitral valvuloplasty nationallicence left ventricular function nationallicence diastolic function nationallicence Razzolini Renato Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut Ramondo Angelo Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut Isabella Giambattista Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut Cardaioli Paolo Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut Campisi Francesco Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut De Leo Alessandro Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut Chioin Raffaello Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut Heart and Vessels Springer-Verlag 11/2(1996-03-01), 86-91 0910-8327 11:2<86 1996 11 380 https://doi.org/10.1007/BF01744508 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01744508 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Razzolini Renato Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut NATIONALLICENCE 700 1- Ramondo Angelo Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut NATIONALLICENCE 700 1- Isabella Giambattista Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut NATIONALLICENCE 700 1- Cardaioli Paolo Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut NATIONALLICENCE 700 1- Campisi Francesco Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut NATIONALLICENCE 700 1- De Leo Alessandro Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut NATIONALLICENCE 700 1- Chioin Raffaello Department of Cardiology and Hemodynamics, Policlinico v. Giustiniani 2, 35128, Padova, Italy aut NATIONALLICENCE 773 0- Heart and Vessels Springer-Verlag 11/2(1996-03-01), 86-91 0910-8327 11:2<86 1996 11 380 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer