caa a22 4500 477113842 CHVBK 20180405111617.0 cr unu---uuuuu 170330e19960101xx s 000 0 eng 10.1007/BF00451974 doi (NATIONALLICENCE)springer-10.1007/BF00451974 Exercise training in older men and women: Effects on cardiovascular and renal function [Elektronische Daten] [James Jessup, David Lowenthal, Michael Pollock, Kathleen Smyth, Leonard Williams, Jorge Ruiz, Michael Fagien, Linda Garzarella] This study investigated the effects of endurance exercise training on cardiovascular and renal function in healthy, older adults. Twenty-three sedentary men and women, 68.2 ± 4.6 (mean ± SD) years of age completed medical screening, including ECG studies and serum chemistries, graded exercise testing, maximal oxygen uptake (VO2max) determinations, and renal function testing prior to being randomly assigned to an exercise group (EG, n = 13), or to a non-exercising control group (CG, n = 10). The EG completed 16 weeks (3-bouts · wk−1) of supervised exercise training on treadmills and stair-climbers, progressing in intensity from 50% to 85% of maximal heart rate reserve. Effective renal plasma flow (ERPF) and glomerular filtration rate (GFR) were measured by single-bolus I.V. radioisotope injections, VO2max was measured during maximum exercise testing. The EG showed a significant increase in VO2max (from 21.8 ml · kg−1 min−1 to 26.0 ml · kg−1 · min−1; p = 0.0009), while the CG showed no change (p = 0.05). There were no significant changes in ERPF or GFR in either group after the 16-wk training or control periods (p > 0.05). These data suggest that although endurance exercise training improves cardiorespiratory function in older adults, renal function is neither improved nor adversely affected. Kluwer Academic Publishers, 1996 aging nationallicence renal function nationallicence exercise nationallicence oxygen consumption nationallicence Jessup James College of Nursing, University of Florida, Gainesville, Florida, USA aut Lowenthal David Veterans Administration Medical Center, Gainesville, Florida, USA aut Pollock Michael Department of Medicine and Center for Exercise Science, University of Florida, Gainesville, Florida, USA aut Smyth Kathleen College of Nursing, University of Florida, Gainesville, Florida, USA aut Williams Leonard Veterans Administration Medical Center, Gainesville, Florida, USA aut Ruiz Jorge Veterans Administration Medical Center, Gainesville, Florida, USA aut Fagien Michael Veterans Administration Medical Center, Gainesville, Florida, USA aut Garzarella Linda Department of Medicine and Center for Exercise Science, University of Florida, Gainesville, Florida, USA aut Geriatric Nephrology and Urology Kluwer Academic Publishers 6/1(1996-01-01), 27-34 0924-8455 6:1<27 1996 6 10715 https://doi.org/10.1007/BF00451974 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00451974 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jessup James College of Nursing, University of Florida, Gainesville, Florida, USA aut NATIONALLICENCE 700 1- Lowenthal David Veterans Administration Medical Center, Gainesville, Florida, USA aut NATIONALLICENCE 700 1- Pollock Michael Department of Medicine and Center for Exercise Science, University of Florida, Gainesville, Florida, USA aut NATIONALLICENCE 700 1- Smyth Kathleen College of Nursing, University of Florida, Gainesville, Florida, USA aut NATIONALLICENCE 700 1- Williams Leonard Veterans Administration Medical Center, Gainesville, Florida, USA aut NATIONALLICENCE 700 1- Ruiz Jorge Veterans Administration Medical Center, Gainesville, Florida, USA aut NATIONALLICENCE 700 1- Fagien Michael Veterans Administration Medical Center, Gainesville, Florida, USA aut NATIONALLICENCE 700 1- Garzarella Linda Department of Medicine and Center for Exercise Science, University of Florida, Gainesville, Florida, USA aut NATIONALLICENCE 773 0- Geriatric Nephrology and Urology Kluwer Academic Publishers 6/1(1996-01-01), 27-34 0924-8455 6:1<27 1996 6 10715 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer