caa a22 4500 477116892 CHVBK 20180405111625.0 cr unu---uuuuu 170330e19960201xx s 000 0 eng 10.1007/BF01874837 doi (NATIONALLICENCE)springer-10.1007/BF01874837 Effect of growth hormone on muscle protein synthesis in rainbow trout ( Oncorhynchus mykiss ) and Atlantic salmon ( Salmo salar ) [Elektronische Daten] [Benoit Fauconneau, Marie Mady, Pierre LeBail] This paper reports on the effect of administration of mammalian growth hormone (GH) on muscle protein synthesis as measured in white muscle using the phenylalanine flooding technique. The effect of exogenous GH was compared with that of insulin and prolactin, and with endogenous GH. The rate of protein synthesis in white muscle of rainbow trout 6 h after the injection of bovine GH or bovine insulin was twice (2.6 and 2.9% d−1) that of the control saline-injected fish (1.2% d−1). A metabolic effect of GH, as observed with insulin, is suspected. The rates of change in body weight and body length and the fractional rate of protein synthesis in muscle of rainbow trout were enhanced by mammalian GH administration. The effect of GH on muscle RNA/protein ratios was not significant. An opposite effect of antibodies against salmon GH (Lebailet al. 1989) on growth rate and muscle protein synthesis rate was found in rainbow trout. It is suggested that the effects of exogenous and endogenous GH on capacity and efficiency of muscle protein synthesis were similar. The long-term effects of mammalian GH on presmolt Atlantic salmon was also tested. The same trends were found with ovine prolactin supplementation in Atlantic salmon but not as high as those observed with ovine GH. Kugler Publication bv, 1996 salmon nationallicence trout nationallicence growth nationallicence growth hormone nationallicence muscle nationallicence protein synthesis nationallicence Fauconneau Benoit Fish Physiology Laboratory, INRA, Campus de Beaulieu, 35042, Rennes Cedex, France aut Mady Marie Fish Physiology Laboratory, INRA, Campus de Beaulieu, 35042, Rennes Cedex, France aut LeBail Pierre Fish Physiology Laboratory, INRA, Campus de Beaulieu, 35042, Rennes Cedex, France aut Fish Physiology and Biochemistry Kluwer Academic Publishers 15/1(1996-02-01), 49-56 0920-1742 15:1<49 1996 15 10695 https://doi.org/10.1007/BF01874837 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01874837 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fauconneau Benoit Fish Physiology Laboratory, INRA, Campus de Beaulieu, 35042, Rennes Cedex, France aut NATIONALLICENCE 700 1- Mady Marie Fish Physiology Laboratory, INRA, Campus de Beaulieu, 35042, Rennes Cedex, France aut NATIONALLICENCE 700 1- LeBail Pierre Fish Physiology Laboratory, INRA, Campus de Beaulieu, 35042, Rennes Cedex, France aut NATIONALLICENCE 773 0- Fish Physiology and Biochemistry Kluwer Academic Publishers 15/1(1996-02-01), 49-56 0920-1742 15:1<49 1996 15 10695 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer