caa a22 4500 477117147 CHVBK 20180405111625.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF01875569 doi (NATIONALLICENCE)springer-10.1007/BF01875569 Distribution of glutamine synthetase in the snapper ( Pagrus auratus ) and implications for the immune system [Elektronische Daten] [S. Walker, D. Keast, S. McBride] A sensitive radiotracer method was used to detect glutamine synthetase activity in fish. The distribution of glutamine synthetase activity using this method was shown to be widespread in organs and tissues of the marine finfish, snapper,Pagrus auratus. The optimum pH and temperature for glutamine synthetase activity and Km of glutamate from the brain of the snapper are also reported. Interestingly no glutamine synthetase activity was detected in lymphoid organs, indicating, that as in the mammal, the teleostean immune system is likely to rely on glutamine in circulation for energy and nucleotide synthesis. Furthermore circulating glutamine levels fell as fish became stressed or became ill. Implications of these observations on the function of the immune system of fish are discussed. Kugler Publication, 1996 glutamine nationallicence glutamine synthetase nationallicence immunity nationallicence stress nationallicence teleost nationallicence fish nationallicence Walker S. Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Australia aut Keast D. Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Australia aut McBride S. Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Australia aut Fish Physiology and Biochemistry Kluwer Academic Publishers 15/3(1996-06-01), 187-194 0920-1742 15:3<187 1996 15 10695 https://doi.org/10.1007/BF01875569 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01875569 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Walker S. Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Australia aut NATIONALLICENCE 700 1- Keast D. Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Australia aut NATIONALLICENCE 700 1- McBride S. Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Australia aut NATIONALLICENCE 773 0- Fish Physiology and Biochemistry Kluwer Academic Publishers 15/3(1996-06-01), 187-194 0920-1742 15:3<187 1996 15 10695 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer