caa a22 4500 477117406 CHVBK 20180405111626.0 cr unu---uuuuu 170330e19960401xx s 000 0 eng 10.1007/BF01875593 doi (NATIONALLICENCE)springer-10.1007/BF01875593 Intraperitoneal injection of sulfur amino acids enhance the hepatic cysteine dioxygenase activity in rainbow trout ( Oncorhynchus mykiss ) [Elektronische Daten] [Masahito Yokoyama, Jun-ichi Nakazoe] As part of the investigation into cysteine metabolism in fish, sulfur amino acids and their derivatives were injected intraperitoneally to fingerling rainbow trout (Oncorhynchus mykiss) to examine how the doses of these compounds affect the hepatic cysteine dioxygenase [EC 1.12.11.20] in this species. A dose of 0.25 mmol L-cysteine per 100 g body weight induced the enzyme activity as much as 2.5 times that of the control fish within 4h after the injection. The activity increased proportionally to the increasing dose of cysteine up to the dose of 0.15 mmol per 100 g body weight. The induction was observed to be rather specific to L-cysteine. These findings suggested that the cysteine sulfinate pathway might play an important role in the metabolism of excess cysteine in rainbow trout. The dosage of L-cysteine larger than 0.50 mmol per 100g body weight led to mortality of the fish. The pathway of cysteine catabolism was considered to function to prevent toxic accumulation of cysteine in rainbow trout, as in the case of mammals. Kugler Publication bv Amsterdam, 1996 sulfur amino acids nationallicence cysteine, cysteine dioxygenase nationallicence rainbow trout nationallicence Oncorhynchus mykiss nationallicence metabolism nationallicence Yokoyama Masahito National Research Institute of Fisheries Science, Ministry of Agriculture, Forestry and Fisheries, Fukuura, Kanazawa-ku, 236, Yokohama, Japan aut Nakazoe Jun-ichi National Research Institute of Fisheries Science, Ministry of Agriculture, Forestry and Fisheries, Fukuura, Kanazawa-ku, 236, Yokohama, Japan aut Fish Physiology and Biochemistry Kluwer Academic Publishers 15/2(1996-04-01), 143-148 0920-1742 15:2<143 1996 15 10695 https://doi.org/10.1007/BF01875593 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01875593 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yokoyama Masahito National Research Institute of Fisheries Science, Ministry of Agriculture, Forestry and Fisheries, Fukuura, Kanazawa-ku, 236, Yokohama, Japan aut NATIONALLICENCE 700 1- Nakazoe Jun-ichi National Research Institute of Fisheries Science, Ministry of Agriculture, Forestry and Fisheries, Fukuura, Kanazawa-ku, 236, Yokohama, Japan aut NATIONALLICENCE 773 0- Fish Physiology and Biochemistry Kluwer Academic Publishers 15/2(1996-04-01), 143-148 0920-1742 15:2<143 1996 15 10695 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer