caa a22 4500 47711850X CHVBK 20180405111629.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF00239316 doi (NATIONALLICENCE)springer-10.1007/BF00239316 Influence of sodium pentosan polysulphate and certain inhibitors on calcium oxalate crystal growth [Elektronische Daten] [D. Senthil, K. Subha, N. Saravanan, P. Varalakshmi] Calcium oxalate crystal growth and aggregation leads to the formation of renal calculi. It is known to be inhibited by several compounds both in vitro and in vivo conditions. The present study highlights the inhibitory potential of sodium pentosan polysulphate (SPP), a semi-synthetic glycosaminoglycan (GAG) on calcium oxalate crystal growth in vitro. Its efficacy was compared with those of known inhibitors like pyrophosphate, heparin and chondroitin-4-sulphate. Of the above compounds pyrophosphate was found to be the most potent inhibitor. Among the GAGs, SPP exhibited 80% inhibitory activity as compared to heparin. A lesser degree of inhibition was observed with chondroitin-4-sulphate. Kluwer Academic Publishers, 1996 glycosaminoglycans nationallicence crystal growth nationallicence pyrophosphate nationallicence inhibitors nationallicence Senthil D. Department of Medical Biochemistry, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, University of Madras, 600 113, Taramani, Madras, India aut Subha K. Department of Medical Biochemistry, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, University of Madras, 600 113, Taramani, Madras, India aut Saravanan N. Department of Medical Biochemistry, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, University of Madras, 600 113, Taramani, Madras, India aut Varalakshmi P. Department of Medical Biochemistry, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, University of Madras, 600 113, Taramani, Madras, India aut Molecular and Cellular Biochemistry Kluwer Academic Publishers 156/1(1996-03-01), 31-35 0300-8177 156:1<31 1996 156 11010 https://doi.org/10.1007/BF00239316 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00239316 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Senthil D. Department of Medical Biochemistry, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, University of Madras, 600 113, Taramani, Madras, India aut NATIONALLICENCE 700 1- Subha K. Department of Medical Biochemistry, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, University of Madras, 600 113, Taramani, Madras, India aut NATIONALLICENCE 700 1- Saravanan N. Department of Medical Biochemistry, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, University of Madras, 600 113, Taramani, Madras, India aut NATIONALLICENCE 700 1- Varalakshmi P. Department of Medical Biochemistry, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, University of Madras, 600 113, Taramani, Madras, India aut NATIONALLICENCE 773 0- Molecular and Cellular Biochemistry Kluwer Academic Publishers 156/1(1996-03-01), 31-35 0300-8177 156:1<31 1996 156 11010 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer