caa a22 4500 477118631 CHVBK 20180405111629.0 cr unu---uuuuu 170330e19960901xx s 000 0 eng 10.1007/BF00426340 doi (NATIONALLICENCE)springer-10.1007/BF00426340 Muscle ubiquinone in healthy physically active males [Elektronische Daten] [Jan Karlsson, Lijun Lin, Christer Sylvén, Eva Jansson] Thirty-five (35) healthy physically active males had muscle biopsies taken from their vastus lateralis muscle to analyze for ubiquinone (vitamin Q, UQ), oxidative (muscle fiber types expressed as %ST and citrate synthase activity, CS) and fermentative (lactate dehydrogenase, LD) profiles. Graded cycle ergometer exercise to determine the intensities corresponding to onset of blood lactate accumulation set to 4.0 mmol × 1−1 (WOBLA) and symptom limited exercise (‘maximal', WSL) were also undertaken. Eleven (11) subjects had also recently participated in a marathon race. UQ was positively related to CS (r = 0.67, p < 0.001) and %ST (r = 0.60, p < 0.001) but not to LD. UQ was also positively related to exercise capacity and/or marathon performance (e.g. WOBLA × kg−1 BW, r = 0.70, p < 0.001). It was suggested that muscle UQ allocation in man was related to variables describing molecular oxygen availability, respiratory activity and oxidative energy releasing processes but not to fermentation activity. UQ allocation to ST fibers/CS activity was suggested to be due to the double role of UQ: 1) as a mitochondrial coenzyme (CoQ10) and 2) as a nonspecific antioxidant. Kluwer Academic Publishers, 1996 physical activity nationallicence antioxidant vitamins nationallicence ubiquinone nationallicence vitamin Q nationallicence muscle fiber types nationallicence muscle oxidative capacity nationallicence oxygen availability nationallicence endurance performance nationallicence Karlsson Jan OBLA AB, Box 242, S-185 23, Vaxholm, Sweden aut Lin Lijun Department of Clinical Physiology, Karolinska Institute, Sweden aut Sylvén Christer Department of Cardiology, Huddinge University Hospital, Karolinska Institute, Sweden aut Jansson Eva Department of Clinical Physiology, Karolinska Institute, Sweden aut Molecular and Cellular Biochemistry Kluwer Academic Publishers 156/2(1996-09-01), 169-172 0300-8177 156:2<169 1996 156 11010 https://doi.org/10.1007/BF00426340 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00426340 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Karlsson Jan OBLA AB, Box 242, S-185 23, Vaxholm, Sweden aut NATIONALLICENCE 700 1- Lin Lijun Department of Clinical Physiology, Karolinska Institute, Sweden aut NATIONALLICENCE 700 1- Sylvén Christer Department of Cardiology, Huddinge University Hospital, Karolinska Institute, Sweden aut NATIONALLICENCE 700 1- Jansson Eva Department of Clinical Physiology, Karolinska Institute, Sweden aut NATIONALLICENCE 773 0- Molecular and Cellular Biochemistry Kluwer Academic Publishers 156/2(1996-09-01), 169-172 0300-8177 156:2<169 1996 156 11010 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer