caa a22 4500 477118860 CHVBK 20180405111630.0 cr unu---uuuuu 170330e19960901xx s 000 0 eng 10.1007/BF00227544 doi (NATIONALLICENCE)springer-10.1007/BF00227544 Glucose is essential for the initiation of fatty acid oxidation in ATP-depleted cultured ventricular myocytes [Elektronische Daten] [Régine Tirosh, Tehila Mishor, Arie Pinson] Cultured cardiac myocytes were depleted of ATP by incubation with oligomycin (1 mg/ml). Then the ability of the cells to oxidize various substrates and to restore ATP levels was studied. Following ATP depletion, the cells were found to be able to oxidize glucose given alone, but not palmitate. However, with both substrates, palmitate was oxidized in the presence of glucose and ATP recovery was enhanced. Pyruvate had a minor effect on palmitate oxidation, while acetate given alone was oxidized, but did not enhance cellular ATP content. These results show that glucose is essential for restoration of mitochondrial function and the coupling between oxidation and ATP synthesis. Kluwer Academic Publishers, 1996 ventricular cardiomyocytes nationallicence oligomycin nationallicence ATP depletion nationallicence glucose oxidation nationallicence fatty acid oxidation nationallicence Tirosh Régine Laboratory for Myocardial Research, Hebrew University - Hadassah Medical School, P.O.B. 12272, 91120, Jerusalem, Israel aut Mishor Tehila Laboratory for Myocardial Research, Hebrew University - Hadassah Medical School, P.O.B. 12272, 91120, Jerusalem, Israel aut Pinson Arie Laboratory for Myocardial Research, Hebrew University - Hadassah Medical School, P.O.B. 12272, 91120, Jerusalem, Israel aut Molecular and Cellular Biochemistry Kluwer Academic Publishers 162/2(1996-09-01), 159-163 0300-8177 162:2<159 1996 162 11010 https://doi.org/10.1007/BF00227544 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00227544 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tirosh Régine Laboratory for Myocardial Research, Hebrew University - Hadassah Medical School, P.O.B. 12272, 91120, Jerusalem, Israel aut NATIONALLICENCE 700 1- Mishor Tehila Laboratory for Myocardial Research, Hebrew University - Hadassah Medical School, P.O.B. 12272, 91120, Jerusalem, Israel aut NATIONALLICENCE 700 1- Pinson Arie Laboratory for Myocardial Research, Hebrew University - Hadassah Medical School, P.O.B. 12272, 91120, Jerusalem, Israel aut NATIONALLICENCE 773 0- Molecular and Cellular Biochemistry Kluwer Academic Publishers 162/2(1996-09-01), 159-163 0300-8177 162:2<159 1996 162 11010 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer