caa a22 4500 477119700 CHVBK 20180405111633.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF00240037 doi (NATIONALLICENCE)springer-10.1007/BF00240037 Repke Kurt Max Delbrück Centre for Molecular Medicine, Robert-Rössle-Str 10, D-13122, Berlin-Buch, Germany aut Reinstatement of the ATP high energy paradigm [Elektronische Daten] [Kurt Repke] The paradigm that the hydrolysis of ATP releases high Gibbs energy able to perform work has increasingly been questioned over the last two decades. Results from theoretical and experimental studies have been interpreted to indicate that the synthesis of ATP from ADP and Pi does not require energy supply and that binding of ATP per se can transmit utilizable energy to an enzyme. As has recently been concluded, all this has led to a change of the ATP high energy paradigm in bioenergetics. Starting from this challenge, the present review singles out the striking sources of the apparent dichotomy in biocnergetics, and endeavours to eliminate the apparent contradictions by the application of the prior knowledge on both the participation of the enzyme protein in energy exchange processes and the particular reactivities of phosphorus that make it an outstanding element for functionally variable work assignments in enzymatic systems. Kluwer Academic Publishers, 1996 ATP synthesis nationallicence ATP hydrolysis nationallicence phosphoryl transfer nationallicence ion-motive force nationallicence energy transfer nationallicence coupling mechanism nationallicence Molecular and Cellular Biochemistry Kluwer Academic Publishers; http://www.wkap.nl 160-161/1(1996-03-01), 95-99 0300-8177 160-161:1<95 1996 160-161 11010 https://doi.org/10.1007/BF00240037 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00240037 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Repke Kurt Max Delbrück Centre for Molecular Medicine, Robert-Rössle-Str 10, D-13122, Berlin-Buch, Germany aut NATIONALLICENCE 773 0- Molecular and Cellular Biochemistry Kluwer Academic Publishers; http://www.wkap.nl 160-161/1(1996-03-01), 95-99 0300-8177 160-161:1<95 1996 160-161 11010 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer