caa a22 4500 477119840 CHVBK 20180405111633.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF00714332 doi (NATIONALLICENCE)springer-10.1007/BF00714332 Gender-related regional antioxidant profiles in the gastrointestinal tract of the rat [Elektronische Daten] [Mohammed Moghadasian, David Godin] This study compared the activities of the antioxidant enzymes glutathione peroxidase, glutathione reductase and superoxide dismutase and the levels of glutathione in the mucosa of the body of the stomach, proximal and distal parts of the small intestine and the colon in male and female Sprague Dawley rats. Basal glutathione levels were significantly (p < 0.05) higher in the small intestine as compared with those in the other portions studied in both sexes. Except for colonic mucosa in females, the activity of glutathione reductase was similar in all the other tissues examined. Glutathione peroxidase showed the largest regional differences, with activities in the gastric segment being several-fold greater than those in small intestine or colon. This enzyme also showed marked gender-related differences, activity being greater in females than males in gastric mucosa and colon, while the converse was true for distal small intestine. In contrast, activities of superoxide dismutase showed minimal regional or gender-dependent variations. Kluwer Academic Publishers, 1996 gastrointestinal mucosa nationallicence glutathione nationallicence glutathione peroxidase nationallicence glutathione reductase nationallicence superoxide dismutase nationallicence Moghadasian Mohammed Department of Pharmacology & Therapeutics, Faculty of Medicine, The University of British Columbia, 2176 Health Sciences Mall, V6T IZ3, B. C., Canada aut Godin David Department of Pharmacology & Therapeutics, Faculty of Medicine, The University of British Columbia, 2176 Health Sciences Mall, V6T IZ3, B. C., Canada aut Molecular and Cellular Biochemistry Kluwer Academic Publishers 155/1(1996-03-01), 43-49 0300-8177 155:1<43 1996 155 11010 https://doi.org/10.1007/BF00714332 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00714332 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Moghadasian Mohammed Department of Pharmacology & Therapeutics, Faculty of Medicine, The University of British Columbia, 2176 Health Sciences Mall, V6T IZ3, B. C., Canada aut NATIONALLICENCE 700 1- Godin David Department of Pharmacology & Therapeutics, Faculty of Medicine, The University of British Columbia, 2176 Health Sciences Mall, V6T IZ3, B. C., Canada aut NATIONALLICENCE 773 0- Molecular and Cellular Biochemistry Kluwer Academic Publishers 155/1(1996-03-01), 43-49 0300-8177 155:1<43 1996 155 11010 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer