caa a22 4500 477119999 CHVBK 20180405111634.0 cr unu---uuuuu 170330e19960401xx s 000 0 eng 10.1007/BF00227880 doi (NATIONALLICENCE)springer-10.1007/BF00227880 Mitogen-activated protein kinase (MAPK) in cardiac tissues [Elektronische Daten] [Carine Page, Anton Doubell] Mitogen-activated protein kinase (MAPK) has recently emerged as a prominent role player in intracellular signalling in the ventricular myocyte with attention being focussed on its possible role in the development of ventricular hypertrophy. It is becoming clear that MAPK is also active in other cells of cardiac origin such as cardiac fibroblasts and possible functions of this signalling pathway in the heart have yet to be explored. In this report the mammalian MAPK pathway is briefly outlined, before reviewing current knowledge of the MAPK pathway in cardiac tissue (ventricular myocytes, vascular smooth muscle cells and cardiac fibroblasts). New data is also presented on the presence and activity of MAPK in two additional cardiac celltypes namely atrial myocytes and vascular endothelial cells from the coronary microcirculation. (Mol Cell Biochem 157: 49-57, 1996) Kluwer Academic Publishers, 1996 MAP kinase nationallicence cardiac nationallicence atrial nationallicence endothelial nationallicence Page Carine Department of Internal Medicine, Faculty of Medicine, University of Stellenbosch, 7505, Tygerberg, South Africa aut Doubell Anton Department of Internal Medicine, Faculty of Medicine, University of Stellenbosch, 7505, Tygerberg, South Africa aut Molecular and Cellular Biochemistry Kluwer Academic Publishers 157/1-2(1996-04-01), 49-57 0300-8177 157:1-2<49 1996 157 11010 https://doi.org/10.1007/BF00227880 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00227880 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Page Carine Department of Internal Medicine, Faculty of Medicine, University of Stellenbosch, 7505, Tygerberg, South Africa aut NATIONALLICENCE 700 1- Doubell Anton Department of Internal Medicine, Faculty of Medicine, University of Stellenbosch, 7505, Tygerberg, South Africa aut NATIONALLICENCE 773 0- Molecular and Cellular Biochemistry Kluwer Academic Publishers 157/1-2(1996-04-01), 49-57 0300-8177 157:1-2<49 1996 157 11010 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer