caa a22 4500 477120318 CHVBK 20180405111635.0 cr unu---uuuuu 170330e19961201xx s 000 0 eng 10.1007/BF00229741 doi (NATIONALLICENCE)springer-10.1007/BF00229741 Lipid metabolism in rats bearing the Yoshida AH-130 ascites hepatoma [Elektronische Daten] [Joaquín López-Soriano, Josep Argilés, Francisco López-Soriano] Rats bearing the Yoshida AH-130 ascites hepatoma showed important changes in lipid metabolism. The presence of this rapidly growing tumour induced a significant reduction in the intestinal absorption of an oral [l4C]triolein load but without changes in whole body oxidation of the tracer to CO3. Both white (WAT) and brown (BAT) adipose tissue lipoprotein lipase (LPL) activities were increased at day 4 of tumour growth, changes that seem to be related with those observed in [14C] lipid accumulation; however, heart LPL activity was increased at day 7 but there was no change at day 4. In addition, there was a marked hyperlipemia in the tumour-bearing animals, whereas the blood ketone body concentrations were lower in these animals in comparison with the corresponding pair-fed group. The in vivo lipogenic rate was increased in liver of the tumour-bearing animals (day 4); conversely, it was decreased in WAT and skeletal muscle (day 4) and IBAT (day 7) of the AH-130-bearing rats. It may be suggested that the increased liver lipogenic rate associated with tumour burden is the main factor contributing to the hyperlipidaemia present in the Yoshida AH-130 bearing rats. Kluwer Academic Publishers, 1996 tumour nationallicence lipid metabolism nationallicence lipoprotein lipase nationallicence lipogenesis nationallicence cachexia nationallicence rat nationallicence López-Soriano Joaquín Departament de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain aut Argilés Josep Departament de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain aut López-Soriano Francisco Departament de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain aut Molecular and Cellular Biochemistry Kluwer Academic Publishers; http://www.wkap.nl 165/1(1996-12-01), 17-23 0300-8177 165:1<17 1996 165 11010 https://doi.org/10.1007/BF00229741 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00229741 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- López-Soriano Joaquín Departament de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain aut NATIONALLICENCE 700 1- Argilés Josep Departament de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain aut NATIONALLICENCE 700 1- López-Soriano Francisco Departament de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain aut NATIONALLICENCE 773 0- Molecular and Cellular Biochemistry Kluwer Academic Publishers; http://www.wkap.nl 165/1(1996-12-01), 17-23 0300-8177 165:1<17 1996 165 11010 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer