caa a22 4500 477125204 CHVBK 20180405111647.0 cr unu---uuuuu 170330e19971201xx s 000 0 eng 10.1007/s004040050191 doi (NATIONALLICENCE)springer-10.1007/s004040050191 The effect of pregnancy on endometriosis in baboons (Papio anubis, Papio cynocephalus) * [Elektronische Daten] [T. M. D'Hooghe, C. S. Bambra, I. De Jonge, J. M. Lauweryns, B. M. Raeymaekers, P. R. Koninckx] Abstract.: Background: This study was performed to test the hypothesis that endometriosis undergoes regression during pregnancy. Methods: This study was performed on 11 baboons with histologically proven endometriosis, housed at the Institute of Primate Research, Nairobi, Kenya. In each individual baboon paired laparoscopies were performed prior to and during pregnancy (6 during first and 5 during second trimester of gestation) with an interval of 5±3 months. During each laparoscopy the number, size and type of endometriosis implants were noted in detail on a pelvic map; the endometriosis score and stage were calculated according to the revised American Fertility Society (AFS) classification. In each baboon the observations prior to and during pregnancy were compared and analysed by Wilcoxon signed rank test (two-tailed). Results: No significant change was observed in the AFS score or stage of endometriosis, or in the number, size and type of endometriotic lesions in baboons during gestation when compared to the nonpregnant state. Conclusion: In baboons pregnancy had no significant effect on endometriosis during the first or second trimester of gestation. Springer-Verlag Berlin Heidelberg, 1997 Key words: Pregnancy nationallicence Gestation nationallicence Endometriosis nationallicence Baboon nationallicence Papio nationallicence Laparoscopy nationallicence D'Hooghe T. M. Department of Reproduction, Institute of Primate Research, PO Box 24481, Nairobi, Kenya, KE aut Bambra C. S. Department of Reproduction, Institute of Primate Research, PO Box 24481, Nairobi, Kenya, KE aut De Jonge I. Department of Histopathology, University Hospital Gasthuisberg, B-3000 Leuven, Belgium, BE aut Lauweryns J. M. Department of Histopathology, University Hospital Gasthuisberg, B-3000 Leuven, Belgium, BE aut Raeymaekers B. M. Department of Reproduction, Institute of Primate Research, PO Box 24481, Nairobi, Kenya, KE aut Koninckx P. R. Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, B-3000 Leuven, Belgium, BE aut https://doi.org/10.1007/s004040050191 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004040050191 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- D'Hooghe T. M. Department of Reproduction, Institute of Primate Research, PO Box 24481, Nairobi, Kenya, KE aut NATIONALLICENCE 700 1- Bambra C. S. Department of Reproduction, Institute of Primate Research, PO Box 24481, Nairobi, Kenya, KE aut NATIONALLICENCE 700 1- De Jonge I. Department of Histopathology, University Hospital Gasthuisberg, B-3000 Leuven, Belgium, BE aut NATIONALLICENCE 700 1- Lauweryns J. M. Department of Histopathology, University Hospital Gasthuisberg, B-3000 Leuven, Belgium, BE aut NATIONALLICENCE 700 1- Raeymaekers B. M. Department of Reproduction, Institute of Primate Research, PO Box 24481, Nairobi, Kenya, KE aut NATIONALLICENCE 700 1- Koninckx P. R. Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, B-3000 Leuven, Belgium, BE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer