caa a22 4500 477125468 CHVBK 20180405111647.0 cr unu---uuuuu 170330e19970101xx s 000 0 eng 10.1007/BF02505315 doi (NATIONALLICENCE)springer-10.1007/BF02505315 A report on 158 cases of transcervical chorionic villus sampling [Elektronische Daten] [H. Salihu, R. Boos, W. Schmidt] Between 1989 and 1994 first trimester transcervical chorionic villus sampling was offered to 158 patients after proper counselling. The gestational age range was 9-12 weeks. The most important indication was advanced maternal age (75.4%). Adequate sampling after two, and a maximum of three attempts, was achieved in 98% and 99.3% of patients respectively. After the first year of the study karyotyping using the direct method alone was successful in 96% of cases. The success of karyotyping cultures was 98%. Excluding one false positive result the rate of fetal karyotypic abnormalities was 4.8%. 5 spontaneous abortions occurred (3.2%), all in patients of advanced maternal age. Moderate or severe vaginal bleeding occured in 6.7% of the patients. There was no case of chorioamnionitis. Springer-Verlag, 1997 Chorionic villus sampling nationallicence Advanced maternal age nationallicence Karyotyping nationallicence Salihu H. Department of Obstetrics and Gynecology, University of Saarland, D-66421, Homburg/Saar, Germany aut Boos R. Department of Obstetrics and Gynecology, University of Saarland, D-66421, Homburg/Saar, Germany aut Schmidt W. Department of Obstetrics and Gynecology, University of Saarland, D-66421, Homburg/Saar, Germany aut Archives of Gynecology and Obstetrics Springer-Verlag 259/2(1997-01-01), 91-95 0932-0067 259:2<91 1997 259 404 https://doi.org/10.1007/BF02505315 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02505315 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Salihu H. Department of Obstetrics and Gynecology, University of Saarland, D-66421, Homburg/Saar, Germany aut NATIONALLICENCE 700 1- Boos R. Department of Obstetrics and Gynecology, University of Saarland, D-66421, Homburg/Saar, Germany aut NATIONALLICENCE 700 1- Schmidt W. Department of Obstetrics and Gynecology, University of Saarland, D-66421, Homburg/Saar, Germany aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 259/2(1997-01-01), 91-95 0932-0067 259:2<91 1997 259 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer