caa a22 4500 477128688 CHVBK 20180405111657.0 cr unu---uuuuu 170330e19970101xx s 000 0 eng 10.1023/A:1018443507512 doi (NATIONALLICENCE)springer-10.1023/A:1018443507512 The risk of breast cancer following spontaneous or induced abortion [Elektronische Daten] [Phyllis Wingo, Kim Newsome, James Marks, Eugenia Calle, Sheryl Parker] To evaluate the relationship between breast cancer risk and spontaneous and induced abortion, we conducted a detailed descriptive review of 32 epidemiologic studies that provided data by type of abortion and by various measures of exposure to abortion-number of abortions, timing of abortion in relation to first full-term pregnancy, length of gestation, and age at first abortion. Breast cancer risk did not appear to be associated with an increasing number of spontaneous or induced abortions. Our review also suggested that breast cancer risk probably was not related to the other measures of exposure to abortion, and probably did not differ by age or a family history of breast cancer. Finally, the data appeared to suggest a slightly increased risk among nulliparous women, but this tendency was based primarily on studies with a small number of nulliparous women who had had spontaneous or induced abortions. Definitive conclusions about an association between breast cancer risk and spontaneous or induced abortion are not possible at present because of inconsistent findings across studies. Future investigations should consider prospective designs, separate analyses of spontaneous and induced abortions, appropriate referent groups, and adequate adjustment for confounding and effect modification. Future investigations also should attempt to determine whether any increased risks reflect the transient increase in breast cancer risk hypothesized for full-term pregnancy or a causal relationship specific to spontaneous or induced abortion. Chapman and Hall, 1997 Abortion nationallicence breast cancer nationallicence pregnancy nationallicence women nationallicence Wingo Phyllis Epidemiology and Surveillance Research, American Cancer Society, Atlanta, USA aut Newsome Kim National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, USA aut Marks James Epidemiology and Surveillance Research, American Cancer Society, Atlanta, USA aut Calle Eugenia Epidemiology and Surveillance Research, American Cancer Society, Atlanta, USA aut Parker Sheryl Epidemiology and Surveillance Research, American Cancer Society, Atlanta, USA aut Cancer Causes & Control Kluwer Academic Publishers 8/1(1997-01-01), 93-108 0957-5243 8:1<93 1997 8 10552 https://doi.org/10.1023/A:1018443507512 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018443507512 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wingo Phyllis Epidemiology and Surveillance Research, American Cancer Society, Atlanta, USA aut NATIONALLICENCE 700 1- Newsome Kim National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, USA aut NATIONALLICENCE 700 1- Marks James Epidemiology and Surveillance Research, American Cancer Society, Atlanta, USA aut NATIONALLICENCE 700 1- Calle Eugenia Epidemiology and Surveillance Research, American Cancer Society, Atlanta, USA aut NATIONALLICENCE 700 1- Parker Sheryl Epidemiology and Surveillance Research, American Cancer Society, Atlanta, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/1(1997-01-01), 93-108 0957-5243 8:1<93 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer