caa a22 4500 477128777 CHVBK 20180405111657.0 cr unu---uuuuu 170330e19971101xx s 000 0 eng 10.1023/A:1018472530653 doi (NATIONALLICENCE)springer-10.1023/A:1018472530653 Testicular cancer and cryptorchidism in relation to prenatal factors: case-control studies in Denmark [Elektronische Daten] [Henrik Møller, Niels Skakkeb\sgmaelig;k] To explore prenatal risk factors that are common to testicular cancer and cryptorchidism, two parallel case-control studies were conducted in Denmark. Information about characteristics of the mother, the pregnancy, and the birth were obtained from the mothers of cases and controls, using a mailed self-administered questionnaire. A maternal age above 30 years was associated with odds ratios (OR) of 1.9 (95 percent confidence interval [CI]= 1.2-3.0) for cryptorchidism and 2.0 (CI = 1.2-3.6) for testicular seminoma; the latter effect was particularly high when the boy was the first child of the mother (OR = 4.1, CI = 1.1-14.6). Birth weights below 3,000 g or above4,000 g were associated with increased risks of testicular cancer, with OR sup to 2.6 (CI = 1.1-5.9) for birth weight below 2,500 g. For cryptorchidism, there was a monotonous trend in the OR from 0.4 in birth weights above 4,500 g to 2.3 in birth weights below 2,500 g. The association between cryptorchidism and testicular cancer was not attenuated by adjustment for maternal age and birthweight, indicating that all three variables are independent risk factors for testicular cancer. With the exception of high maternal age, which consistently is associated more strongly with seminoma than withnon-seminoma, it remains most likely that seminoma and non-seminoma have similar causes. Chapman and Hall, 1997 Cryptorchidism nationallicence Denmark nationallicence men nationallicence testicular neoplasms nationallicence Møller Henrik Centre for Research in Health & Social Statistics, The Danish National Research Foundation, Copenhagen, Denmark aut Skakkeb\sgmaelig;k Niels Department of Growth and Reproduction, National University Hospital, Copenhagen, Denmark aut Cancer Causes & Control Kluwer Academic Publishers 8/6(1997-11-01), 904-912 0957-5243 8:6<904 1997 8 10552 https://doi.org/10.1023/A:1018472530653 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018472530653 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Møller Henrik Centre for Research in Health & Social Statistics, The Danish National Research Foundation, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Skakkeb\sgmaelig;k Niels Department of Growth and Reproduction, National University Hospital, Copenhagen, Denmark aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/6(1997-11-01), 904-912 0957-5243 8:6<904 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer