caa a22 4500 477128831 CHVBK 20180405111657.0 cr unu---uuuuu 170330e19971101xx s 000 0 eng 10.1023/A:1018460227927 doi (NATIONALLICENCE)springer-10.1023/A:1018460227927 Plantar melanoma: a case-control study in Paraguay [Elektronische Daten] [P.A. Rolón, E. Kramárová, H.I. Rolón, M. Khlat, D.M. Parkin] In Paraguay, the plantar surface of the foot is the most common site for malignant melanoma, as it is in several other populations worldwide, most notably in those of African descent. Here, we report the results of the first case-control study of plantar melanoma, carried out in Paraguay. Sixty incident, histologically confirmed cases of plantar melanoma and 256 hospital controls were recruited in 11 hospitals throughout the country during1988-93. Information was collected on general demographic, social, and lifestyle variables, on external exposures of feet (shoe wear, work activities,injuries),and on some constitutional factors (skin, eye and haircolor,and pigmented lesions of the feet). Few of the factors examined appeared to be associated with the risk of plantar melanoma. Adjusted for possible confounders, the strongest association was found for reported injuries (odds ratio [OR] = 40.9, 95 percent confidence interval [CI] = 14.8-112.7) and for occurrence of naevi on the soles (OR = 5.9, CI = 2.5-14.3). Walking barefoot did not seem to contribute to the risk although an outdoor workplace was associated with an increased melanoma occurrence (OR = 2.3, CI = 1.1-4.8).Future studies should be aware of problems of recall bias with respect to previous injuries, and ensure that evaluation of pigmentation of the sole is carried out blind to case/control status. Chapman and Hall, 1997 Case-control study nationallicence Paraguay nationallicence plantar melanoma nationallicence Rolón P.A. Faculty of Medicine in the University of Asunción, Paraguay aut Kramárová E. Cancer Research Institute of Slovak Academy of Sciences, Bratislava, Slovakia aut Rolón H.I. Faculty of Medicine in the University of Asunción, Paraguay aut Khlat M. International Agency for Research on Cancer, Lyon, France aut Parkin D.M. Unit of Descriptive Epidemiology, International Agency for Research on Cancer, Lyon, France aut Cancer Causes & Control Kluwer Academic Publishers 8/6(1997-11-01), 850-856 0957-5243 8:6<850 1997 8 10552 https://doi.org/10.1023/A:1018460227927 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018460227927 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rolón P.A. Faculty of Medicine in the University of Asunción, Paraguay aut NATIONALLICENCE 700 1- Kramárová E. Cancer Research Institute of Slovak Academy of Sciences, Bratislava, Slovakia aut NATIONALLICENCE 700 1- Rolón H.I. Faculty of Medicine in the University of Asunción, Paraguay aut NATIONALLICENCE 700 1- Khlat M. International Agency for Research on Cancer, Lyon, France aut NATIONALLICENCE 700 1- Parkin D.M. Unit of Descriptive Epidemiology, International Agency for Research on Cancer, Lyon, France aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/6(1997-11-01), 850-856 0957-5243 8:6<850 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer