caa a22 4500 477128858 CHVBK 20180405111657.0 cr unu---uuuuu 170330e19971101xx s 000 0 eng 10.1023/A:1018424614723 doi (NATIONALLICENCE)springer-10.1023/A:1018424614723 Dietary fat and lung cancer: a case-control study in Uruguay [Elektronische Daten] [Eduardo De Stefani, Hugo Deneo-Pellegrini, Maria Mendilaharsu, Julio Carzoglio, Alvaro Ronco] To examine whether dietary fat and cholesterol modifies lung cancer risk, a case-control study was conducted in Uruguay of 426 men diagnosed from1993 to 1996 with lung cancer, and 419 hospitalized frequency-matched controls. Dietary patterns were assessed using a 64-item food frequency questionnaire, which allowed the calculation of total energy intake. After adjustment for potential confounders through a model which included tobacco smoking, total energy, a term for all vegetables and fruits, and a-carotene in take, an increase in risk for total fat intake for all cell types of lung cancer was observed. Adenocarcinoma of the lung was associated strongly with saturated fat intake (odds ratio [OR] = 2.3, 95 percent confidence interval[CI] = 1.2-4.4), whereas small-cell lung cancer was associated with dietary cholesterol (OR = 2.8, CI = 1.1-7.5). These results suggest that the association of saturated fat and cholesterol could be type-specific, but the high correlation existing between dietary lipids precludes any strong statement about this point. Chapman and Hall, 1997 Diet nationallicence fat nationallicence lung cancer nationallicence men nationallicence Uruguay nationallicence De Stefani Eduardo Registro Nacional de Cancer, Montevideo, Uruguay aut Deneo-Pellegrini Hugo Laboratoria de Anatomia Patologica, Instituto Nacional de Oncologia, Montevideo, Uruguay aut Mendilaharsu Maria Registro Nacional de Cancer, Montevideo, Uruguay aut Carzoglio Julio Laboratoria de Anatomia Patologica, Instituto Nacional de Oncologia, Montevideo, Uruguay aut Ronco Alvaro Registro Nacional de Cancer, Montevideo, Uruguay aut Cancer Causes & Control Kluwer Academic Publishers 8/6(1997-11-01), 913-921 0957-5243 8:6<913 1997 8 10552 https://doi.org/10.1023/A:1018424614723 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018424614723 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- De Stefani Eduardo Registro Nacional de Cancer, Montevideo, Uruguay aut NATIONALLICENCE 700 1- Deneo-Pellegrini Hugo Laboratoria de Anatomia Patologica, Instituto Nacional de Oncologia, Montevideo, Uruguay aut NATIONALLICENCE 700 1- Mendilaharsu Maria Registro Nacional de Cancer, Montevideo, Uruguay aut NATIONALLICENCE 700 1- Carzoglio Julio Laboratoria de Anatomia Patologica, Instituto Nacional de Oncologia, Montevideo, Uruguay aut NATIONALLICENCE 700 1- Ronco Alvaro Registro Nacional de Cancer, Montevideo, Uruguay aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/6(1997-11-01), 913-921 0957-5243 8:6<913 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer