caa a22 4500 477129005 CHVBK 20180405111658.0 cr unu---uuuuu 170330e19970501xx s 000 0 eng 10.1023/A:1018401120233 doi (NATIONALLICENCE)springer-10.1023/A:1018401120233 Risk of lung cancer from environmental exposures to tobacco smoke [Elektronische Daten] [Douglas Dockery, Dimitrios Trichopoulos] Epidemiologic evidence on the relation between environmental tobacco smoke and cancer is reviewed. The labeling of tobacco smoke as an environmental cause of lung cancer has been challenged based on allegations of bias in the epidemiologic data. However, tobacco smoke has been shown to increase the risk of lung cancer down to the lowest exposure levels. Environmental tobacco smoke contains the same carcinogenic compounds as those found in the tobacco smoke inhaled directly by the smoker. Nonsmokers environmentally exposed have elevated levels of tobacco smoke byproducts in biological samples. These observations alone are sufficient to identify tobacco smoke as an environmental carcinogen. The epidemiologic studies showing that environmental exposure to tobacco smoke is associated weakly but consistently with increased risk of lung cancer. While these epidemiologic studies have been challenged, it does not appear that the observed epidemiologic associations are due to misclassification or confounding. Indeed, the epidemiologic results, particularly among the studies with superior data collection methods and better control of bias and confounding, find consistent associations between environmental tobacco smoke and lung cancer. This paper summarizes the evidence that environmental exposure to tobacco smoke increases the risk of lung cancer, and considers the criticisms of the epidemiologic evidence which have been raised. Chapman and Hall, 1997 Environmental tobacco smoke nationallicence lung cancer nationallicence smoking nationallicence Dockery Douglas Environmental Epidemiology Program, Harvard School of Public Health, Boston, USA aut Trichopoulos Dimitrios Department of Epidemiology and the Harvard Center for Cancer Prevention, Harvard School of Public Health, Boston, USA aut Cancer Causes & Control Kluwer Academic Publishers 8/3(1997-05-01), 333-345 0957-5243 8:3<333 1997 8 10552 https://doi.org/10.1023/A:1018401120233 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018401120233 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dockery Douglas Environmental Epidemiology Program, Harvard School of Public Health, Boston, USA aut NATIONALLICENCE 700 1- Trichopoulos Dimitrios Department of Epidemiology and the Harvard Center for Cancer Prevention, Harvard School of Public Health, Boston, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/3(1997-05-01), 333-345 0957-5243 8:3<333 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer