caa a22 4500 477129080 CHVBK 20180405111658.0 cr unu---uuuuu 170330e19970501xx s 000 0 eng 10.1023/A:1018413522959 doi (NATIONALLICENCE)springer-10.1023/A:1018413522959 Pesticides and cancer [Elektronische Daten] [Jan Dich, Shelia Zahm, Annika Hanberg, Hans-Olov Adami] Epidemiologic evidence on the relationship between chemical pesticides and cancer is reviewed. In animal studies, many pesticides are carcinogenic, (e.g., organochlorines, creosote, and sulfallate) while others (notably, the organochlorines DDT, chlordane, and lindane) are tumor promoters. Some contaminants in commercial pesticide formulations also may pose a carcinogenic risk. In humans, arsenic compounds and insecticides used occupationally have been classified as carcinogens by the International Agency for Research on Cancer. Human data, however, are limited by the small number of studies that evaluate individual pesticides. Epidemiologic studies, although some-times contradictory, have linked phenoxy acid herbicides or contaminants in them with soft tissue sarcoma (STS) and malignant lymphoma; organochlorine insecticides are linked with STS, non-Hodgkin's lymphoma (NHL), leukemia, and, less consistently, with cancers of the lung and breast; organophosphorous compounds are linked with NHL and leukemia; and triazine herbicides with ovarian cancer. Few, if any, of these associations can be considered established and causal. Hence, further epidemiologic studies are needed with detailed exposure assessment for individual pesticides, taking into consideration work practices, use of protective equipment, and other measures to reduce risk. Chapman and Hall, 1997 Malignant lymphoma nationallicence occupational exposure nationallicence soft tissue sarcoma nationallicence Dich Jan Department of Cancer Epidemiology, Institution of Oncology-Pathology, Karolinska Institute and Radiumhemmet, Karolinska University Hospital, Stockholm, Sweden aut Zahm Shelia Environmental Epidemiology Branch, US National Cancer Institute, Bethesda, USA aut Hanberg Annika Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden aut Adami Hans-Olov Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden aut Cancer Causes & Control Kluwer Academic Publishers 8/3(1997-05-01), 420-443 0957-5243 8:3<420 1997 8 10552 https://doi.org/10.1023/A:1018413522959 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018413522959 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dich Jan Department of Cancer Epidemiology, Institution of Oncology-Pathology, Karolinska Institute and Radiumhemmet, Karolinska University Hospital, Stockholm, Sweden aut NATIONALLICENCE 700 1- Zahm Shelia Environmental Epidemiology Branch, US National Cancer Institute, Bethesda, USA aut NATIONALLICENCE 700 1- Hanberg Annika Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden aut NATIONALLICENCE 700 1- Adami Hans-Olov Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/3(1997-05-01), 420-443 0957-5243 8:3<420 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer