caa a22 4500 477129277 CHVBK 20180405111700.0 cr unu---uuuuu 170330e19970701xx s 000 0 eng 10.1023/A:1018458700185 doi (NATIONALLICENCE)springer-10.1023/A:1018458700185 Physical activity and reduced risk of colon cancer: implications for prevention [Elektronische Daten] [Graham Colditz, Carolyn Cannuscio, A. Frazier] This paper reviews the consistency of the relation between increasedphysical activity and reduced risk of colon cancer, estimates the potentialprevention benefit from increasing population levels of physical activity,and considers social strategies to increase activity levels. The publishedliterature was reviewed systematically and supplemented by MEDLINE searchesthrough March 1997. Studies that reported a measure of physical activity andoutcomes of colon cancer or colorectal cancer were included. We excluded thefirst report of a study that was expanded subsequently by extended follow-up,and any study that did not report the methods for measurement of physicalactivity. Data were extracted including details on study size, methods ofclassifying physical activity, and outcomes. A consistent inverse relationwas observed such that increased physical activity was associated withreduced risk of colon cancer. About a 50 percent reduction in incidence wasobserved among thos e with the highest level of activity across numerousstudies that used different measures of activity (occupational orleisure-time activity). This association persisted in studies usingmultivariate analyses to control for diet and other known or suspected riskfactors for colon cancer. Risk reduction was attenuated in those studies thatcombined colon and rectal cancer. This review indicates that greaterattention should be placed on social strategies to increase physical activityas a means of preventing colon cancer. Chapman and Hall, 1997 Colon cancer nationallicence physical activity nationallicence prevention nationallicence Colditz Graham Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, USA aut Cannuscio Carolyn Department of Health and Social Behavior, Harvard School of Public Health, Boston, USA aut Frazier A. Pediatric Oncology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, USA aut Cancer Causes & Control Kluwer Academic Publishers 8/4(1997-07-01), 649-667 0957-5243 8:4<649 1997 8 10552 https://doi.org/10.1023/A:1018458700185 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018458700185 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Colditz Graham Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, USA aut NATIONALLICENCE 700 1- Cannuscio Carolyn Department of Health and Social Behavior, Harvard School of Public Health, Boston, USA aut NATIONALLICENCE 700 1- Frazier A. Pediatric Oncology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/4(1997-07-01), 649-667 0957-5243 8:4<649 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer