caa a22 4500 47712934X CHVBK 20180405111700.0 cr unu---uuuuu 170330e19970901xx s 000 0 eng 10.1023/A:1018419118841 doi (NATIONALLICENCE)springer-10.1023/A:1018419118841 Parental occupation, occupational exposure to solvents and polycyclic aromatic hydrocarbons and risk of childhood brain tumors (Italy, France, Spain) [Elektronische Daten] [S. Cordier, B. Lefeuvre, G. Filippini, R. Peris-Bonet, M. Farinotti, G. Lovicu, L. Mandereau] The role of parental occupational exposure in childhood brain tumorswas investigated in a population-based case-control study grouping 251 casesand 601 controls from three European centers: Milan (Italy), Paris (France),and Valencia (Spain). Parental occupational exposure to solvents andpolycyclic aromatic hydrocarbons (PAH) during the five-year period beforebirth was estimated using a job-exposure matrix developed earlier in the samecountries. Odds ratios (OR) of brain tumors for each occupation andoccupational exposure were estimated by logistic regression, adjusting forchild's age, gender, exposure to tobacco smoke and ionizing radiation,mother's age and years of schooling, and center. The risk of childhood braintumors rose when fathers worked in agriculture (OR = 2.2, 95 percentconfidence interval [CI] = 1.0-4.7) and motor-vehicle-related occupations. Inthe latter group, the risk increased for primitive neuroectodermal tumors inparticular (OR = 2.7, CI = 1.1-6. 6). Astroglial tumors were more frequentamong children of mothers in health services (OR = 2.2, CI = 1.0-4.9).Paternal exposure to PAHs was associated with an increased, but notdose-related, risk of primitive neuroectodermal tumors (OR = 2.0, CI =1.0-4.0), and maternal exposure to solvents at a high level was associatedwith an increased risk of both astroglial (OR = 2.3, CI = 0.9-5.8) andprimitive neuroectodermal tumors (OR = 3.2, CI = 1.0-10.3). Chapman and Hall, 1997 Brain neoplasms nationallicence child nationallicence Europe nationallicence parental occupation nationallicence polycyclic aromatic hydrocarbons nationallicence solvents nationallicence Cordier S. Unit of Epidemiological and Statistical Research on Environment and Health, National Institute of Health and Medical Research (INSERM), Villejuif, France aut Lefeuvre B. Unit of Epidemiological and Statistical Research on Environment and Health, National Institute of Health and Medical Research (INSERM), Villejuif, France aut Filippini G. Istituto Neurologico ‘C. Besta', Milan, Italy aut Peris-Bonet R. Universitat de Valencia, Valencia, Spain aut Farinotti M. Istituto Neurologico ‘C. Besta', Milan, Italy aut Lovicu G. Istituto Neurologico ‘C. Mondino', Pavia, Italy aut Mandereau L. Unit of Epidemiological and Statistical Research on Environment and Health, National Institute of Health and Medical Research (INSERM), Villejuif, France aut Cancer Causes & Control Kluwer Academic Publishers 8/5(1997-09-01), 688-697 0957-5243 8:5<688 1997 8 10552 https://doi.org/10.1023/A:1018419118841 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018419118841 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cordier S. Unit of Epidemiological and Statistical Research on Environment and Health, National Institute of Health and Medical Research (INSERM), Villejuif, France aut NATIONALLICENCE 700 1- Lefeuvre B. Unit of Epidemiological and Statistical Research on Environment and Health, National Institute of Health and Medical Research (INSERM), Villejuif, France aut NATIONALLICENCE 700 1- Filippini G. Istituto Neurologico ‘C. Besta', Milan, Italy aut NATIONALLICENCE 700 1- Peris-Bonet R. Universitat de Valencia, Valencia, Spain aut NATIONALLICENCE 700 1- Farinotti M. Istituto Neurologico ‘C. Besta', Milan, Italy aut NATIONALLICENCE 700 1- Lovicu G. Istituto Neurologico ‘C. Mondino', Pavia, Italy aut NATIONALLICENCE 700 1- Mandereau L. Unit of Epidemiological and Statistical Research on Environment and Health, National Institute of Health and Medical Research (INSERM), Villejuif, France aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/5(1997-09-01), 688-697 0957-5243 8:5<688 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer