caa a22 4500 477129412 CHVBK 20180405111700.0 cr unu---uuuuu 170330e19970901xx s 000 0 eng 10.1023/A:1018475203820 doi (NATIONALLICENCE)springer-10.1023/A:1018475203820 Dietary relationships with early onset (under age 45) breast cancer in a case-control study in the United States: influence of chemotherapy treatment [Elektronische Daten] [N. Potischman, C. Swanson, R. Coates, H. Weiss, D. Brogan, J. Stanford, J. Schoenberg, M. Gammon, L. Brinton] Methodologic investigations have addressed selection and recall biasin case-control studies of diet and breast cancer, whereas the effect ofdisease progression and medical treatment on estimates of dietary intake hasbeen largely overlooked. In a multicenter, population-based case-controlstudy of breast cancer in the United States, 1,588 newly diagnosed cases and1,451 controls completed a self-administered food-frequency questionnaire.Initial evaluation suggested increased risk related to high intakes ofcalories, carbohydrates, fat, and protein. All nutrient associations werediminished after adjustment for calories. Evaluation by stage of diseaserevealed no relation of calories to risk among women with in situ disease,but elevated risks among women with localized (odds ratio [OR] = 1.33, 95percent confidence interval [CI] = 1.0-1.7 highest cf lowest quartile) orregional and distant disease (OR = 1.79, CI = 1.3-2.4). Further evaluationshowed that the increased risk a ssociated with calories was restricted tocases who reported having been treated with chemotherapy (OR = 1.66, CI =1.3-2.1). A gradient of increasing risk with time interval from diagnosis tointerview suggested the chemotherapy regimen itself and not necessarilycharacteristics of tumors requiring this treatment was responsible for theobserved increased risk. These results indicate that epidemiologic studies ofdiet and breast cancer, particularly among young women, should evaluatepossible bias related to post-diagnosis influences. Chapman and Hall, 1997 Breast cancer nationallicence chemotherapy nationallicence diet nationallicence United States nationallicence women nationallicence Potischman N. Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA aut Swanson C. Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA aut Coates R. Division of Cancer Prevention and Control, Centers for Disease Control, Atlanta, USA aut Weiss H. Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA aut Brogan D. Rollins School of Public Health, Emory University, Atlanta, USA aut Stanford J. Utah Cancer Registry, Salt Lake City, USA aut Schoenberg J. New Jersey Department of Health and Senior Services, Trenton, USA aut Gammon M. Columbia School of Public Health, New York, USA aut Brinton L. Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA aut Cancer Causes & Control Kluwer Academic Publishers 8/5(1997-09-01), 713-721 0957-5243 8:5<713 1997 8 10552 https://doi.org/10.1023/A:1018475203820 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018475203820 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Potischman N. Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA aut NATIONALLICENCE 700 1- Swanson C. Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA aut NATIONALLICENCE 700 1- Coates R. Division of Cancer Prevention and Control, Centers for Disease Control, Atlanta, USA aut NATIONALLICENCE 700 1- Weiss H. Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA aut NATIONALLICENCE 700 1- Brogan D. Rollins School of Public Health, Emory University, Atlanta, USA aut NATIONALLICENCE 700 1- Stanford J. Utah Cancer Registry, Salt Lake City, USA aut NATIONALLICENCE 700 1- Schoenberg J. New Jersey Department of Health and Senior Services, Trenton, USA aut NATIONALLICENCE 700 1- Gammon M. Columbia School of Public Health, New York, USA aut NATIONALLICENCE 700 1- Brinton L. Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/5(1997-09-01), 713-721 0957-5243 8:5<713 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer