caa a22 4500 477129455 CHVBK 20180405111700.0 cr unu---uuuuu 170330e19970901xx s 000 0 eng 10.1023/A:1018490212481 doi (NATIONALLICENCE)springer-10.1023/A:1018490212481 Plant foods and colon cancer: an assessment of specific foods and their related nutrients (United States) [Elektronische Daten] [Martha Slattery, John Potter, Ashley Coates, Khe-Ni Ma, T. Berry, Debra Duncan, Bette Caan] Plant foods have been associated inversely with colon cancer. Since amajor focus of this study was to identify components of plant foods whichmay account for their association with colon cancer, nutrients which arecommonly found in plant foods also were evaluated. A population-basedcase-control study was conducted in Northern California, Utah, and the ‘TwinCities' area of Minnesota (United States). Complete data were available frominterviewer-administered questionnaires on 1,993 cases and 2,410 controls.Higher intakes of vegetables (for highest relative to lowest quintile ofintake) were associated inversely with colon cancer risk: the odds ratio(OR) was 0.7 for both men (95 percent [CI] confidence interval = 0.5-0.9)and women (CI = 0.5-1.0). Associations were stronger among those withproximal tumors. Total fruit intake was not associated with colon cancerrisk although, among men, higher levels of whole grain intake wereassociated with a decreased risk (OR = 0.6, CI = 0.4-0.9 for older men);high intakes of refined grains were associated with an increased risk (OR =1.5, CI = 1.1-2.1). Dietary fiber intake was associated with a decreasedrisk of colon cancer: OR = 0.5 (CI = 0.3-0.9) for older men; OR = 0.7 (CI =0.4-1.2) for older women; OR = 0.6 (CI = 0.4-1.0) for men with proximaltumors; OR = 0.5 (CI = 0.3-0.9) for women with proximal tumors. Othernutrients, for which plant foods were the major contributor - such asvitamin B6, thiamin, and niacin (women only) - also were associatedinversely with colon cancer. Neither beta-carotene nor vitamin C wasprotective for colon cancer. Adjustment of plant foods for nutrients foundin plant foods or for supplement use did not appreciably alter the observedassociations between plant foods and colon cancer. Chapman and Hall, 1997 beta-carotene nationallicence colon cancer nationallicence dietary fiber nationallicence folate nationallicence fruits nationallicence thiamin nationallicence United States nationallicence vegetables nationallicence vitamin C nationallicence vitamin B6 nationallicence whole grains nationallicence Slattery Martha the Department of Oncological Sciences, University of Utah, Salt Lake City, USA aut Potter John Fred Hutchinson Cancer Research Center, Seattle, USA aut Coates Ashley Division of Research, Kaiser Permanente Medical Care Program, Oakland, USA aut Ma Khe-Ni the Department of Oncological Sciences, University of Utah, Salt Lake City, USA aut Berry T. the Department of Oncological Sciences, University of Utah, Salt Lake City, USA aut Duncan Debra Division of Research, Kaiser Permanente Medical Care Program, Oakland, USA aut Caan Bette Division of Research, Kaiser Permanente Medical Care Program, Oakland, USA aut Cancer Causes & Control Kluwer Academic Publishers 8/5(1997-09-01), 575-590 0957-5243 8:5<575 1997 8 10552 https://doi.org/10.1023/A:1018490212481 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018490212481 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Slattery Martha the Department of Oncological Sciences, University of Utah, Salt Lake City, USA aut NATIONALLICENCE 700 1- Potter John Fred Hutchinson Cancer Research Center, Seattle, USA aut NATIONALLICENCE 700 1- Coates Ashley Division of Research, Kaiser Permanente Medical Care Program, Oakland, USA aut NATIONALLICENCE 700 1- Ma Khe-Ni the Department of Oncological Sciences, University of Utah, Salt Lake City, USA aut NATIONALLICENCE 700 1- Berry T. the Department of Oncological Sciences, University of Utah, Salt Lake City, USA aut NATIONALLICENCE 700 1- Duncan Debra Division of Research, Kaiser Permanente Medical Care Program, Oakland, USA aut NATIONALLICENCE 700 1- Caan Bette Division of Research, Kaiser Permanente Medical Care Program, Oakland, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Kluwer Academic Publishers 8/5(1997-09-01), 575-590 0957-5243 8:5<575 1997 8 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer