caa a22 4500 477132294 CHVBK 20180405111707.0 cr unu---uuuuu 170330e19970301xx s 000 0 eng 10.1023/A:1018397031232 doi (NATIONALLICENCE)springer-10.1023/A:1018397031232 Proferrorosamines and phytopathogenicity in Erwinia spp [Elektronische Daten] [Gottfried Feistner, Athanassios Mavridis, Klaus Rudolph] Proferrorosamine A (pFR A) of the plant pathogenic bacterium Erwinia rhapontici was shown to inhibit growth of wheat and cress seedlings at the ≥ 10 ppm level. When the seeds were continuously exposed to 100 ppm pFR A, the germination of cress and wheat seeds was inhibited up to 90% and 80%, respectively. The inhibition could be reversed through addition of equimolar amounts of ferrous iron, which indicates that the strong iron chelating capability of pFR A is responsible for the observed effect. The Fe(II) in the corresponding iron complex, ferrorosamine A, was found to be remarkably resistant towards oxidation by hydrogen peroxide and therefore redox-cycling in the Haber-Weiss cycle. It is thus conceivable that pFR A may also attenuate the generation of reactive hydroxyl radicals during the resistant and wound reaction. The apparent correlation between proferrorosamine production and virulence in erwiniae was further corroborated through the analysis of Erwinia persicinus, a newly described species. Using electrospray ionization mass spectrometry, E. persicinus was shown to produce pFR A and pFR B, and preliminary evidence for the phytopathogenicity of E. persicinus was found in cress. Inhibition of wheat seedlings by E. persicinus could not be demonstrated, but this may be due to technical difficulties or different host specificities. Taken together, our results indicate that the phytopathogenicity of E. rhapontici and E. persicinus may, as least in part, be due to the release of proferrorosamines. Chapman and Hall, 1997 bacterial diseases nationallicence metabolic profiling nationallicence phytotoxicity nationallicence pigments nationallicence siderophores nationallicence Feistner Gottfried Beckman Research Institute, City of Hope Duarte, CA, USA aut Mavridis Athanassios Beckman Research Institute, City of Hope Duarte, CA, USA aut Rudolph Klaus Beckman Research Institute, City of Hope Duarte, CA, USA aut Biometals Kluwer Academic Publishers 10/1(1997-03-01), 1-10 0966-0844 10:1<1 1997 10 10534 https://doi.org/10.1023/A:1018397031232 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018397031232 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Feistner Gottfried Beckman Research Institute, City of Hope Duarte, CA, USA aut NATIONALLICENCE 700 1- Mavridis Athanassios Beckman Research Institute, City of Hope Duarte, CA, USA aut NATIONALLICENCE 700 1- Rudolph Klaus Beckman Research Institute, City of Hope Duarte, CA, USA aut NATIONALLICENCE 773 0- Biometals Kluwer Academic Publishers 10/1(1997-03-01), 1-10 0966-0844 10:1<1 1997 10 10534 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer