caa a22 4500 477132626 CHVBK 20180405111708.0 cr unu---uuuuu 170330e19970601xx s 000 0 eng 10.1023/A:1018327122629 doi (NATIONALLICENCE)springer-10.1023/A:1018327122629 Siderophore activity of chemically synthesized dihydroxybenzoyl derivatives of spermidines and cystamide [Elektronische Daten] [Rolf Reissbrodt, Florence Ramiandrasoa, Laurent Bricard, Gerhard Kunesch] Chemically synthesized dihydroxybenzoyl derivatives of spermidine and cystamide containing two-, three- and four-bidentates with the hydroxyl groups in 2,3 or 3,4 position were examined in cross-feeding tests using Gram-negative siderophore indicator strains carrying different iron-related markers, and two Mycobacterium spp. The catecholates were unable to feed tonB mutants of E. coli and S. typhimurium as well as the fepA, fiu, cir mutant of E. coli, pointing to a tonB- and fepA, cir, fiu-dependent transport. Bis(2,3-dihydroxybenzoyl)derivatives promoted Salmonella spp, E. coli, K. pneumoniae and P. aeruginosa strains significantly better than did 3,4-dihydroxybenzoyl derivatives. N-substituted spermidines acted more effectively than non-substituted derivatives. Bis(2,3-dihydroxybenzoyl) cystamide was superior to the other catecholates tested in growth promotion of Gram-negative bacteria. The two four-bidentates and the tri-bidentate reacted to K. pneumoniae in an inhibitory mode. The position of the hydroxyl groups did not significantly influence the growth promotion of M. smegmatis and M. fortiutum in the cases of substituted spermidines and of cystamides. Chapman and Hall, 1997 dihydroxybenzoylcystamides nationallicence dihydroxybenzoylspermidines nationallicence Gram-negative bacteria nationallicence Mycobacterium spp nationallicence siderophore activity nationallicence Reissbrodt Rolf Robert Koch-Institut, Bereich Wernigerode Wernigerode, Germany aut Ramiandrasoa Florence Institut de Chimie Mole´culaire dÕOrsay, Universite´ de Paris XI, Paris, France aut Bricard Laurent Institut de Chimie Mole´culaire dÕOrsay, Universite´ de Paris XI, Paris, France aut Kunesch Gerhard Institut de Chimie Mole´culaire dÕOrsay, Universite´ de Paris XI, Paris, France aut Biometals Kluwer Academic Publishers 10/2(1997-06-01), 95-103 0966-0844 10:2<95 1997 10 10534 https://doi.org/10.1023/A:1018327122629 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018327122629 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Reissbrodt Rolf Robert Koch-Institut, Bereich Wernigerode Wernigerode, Germany aut NATIONALLICENCE 700 1- Ramiandrasoa Florence Institut de Chimie Mole´culaire dÕOrsay, Universite´ de Paris XI, Paris, France aut NATIONALLICENCE 700 1- Bricard Laurent Institut de Chimie Mole´culaire dÕOrsay, Universite´ de Paris XI, Paris, France aut NATIONALLICENCE 700 1- Kunesch Gerhard Institut de Chimie Mole´culaire dÕOrsay, Universite´ de Paris XI, Paris, France aut NATIONALLICENCE 773 0- Biometals Kluwer Academic Publishers 10/2(1997-06-01), 95-103 0966-0844 10:2<95 1997 10 10534 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer