caa a22 4500 477136435 CHVBK 20180405111719.0 cr unu---uuuuu 170330e19970401xx s 000 0 eng 10.1023/A:1018639211400 doi (NATIONALLICENCE)springer-10.1023/A:1018639211400 Identification of spin diffusion pathways in proteins by isotope-assisted NMR cross- relaxation network editing [Elektronische Daten] [Nenad Juranic, Zsolt Zolnai, Slobodan Macura] A new isotope-assisted cross-relaxation editing experiment, [1H-13C]DINE-NOESY[1H-15N]HSQC (DINE = Double INEPT Edited), is proposed. It is based on the selectiveinversion of CH/CH3 or CH2 protons in the middle of the mixing time. The experiment sortsout the spin diffusion paths according to the principal mediators, either the CH/CH3 or theCH2 protons. This is useful in the structure refinement process, as it enables proper alignmentof the aliphatic protons in the vicinity of NH protons. Kluwer Academic Publishers, 1997 NOESY editing nationallicence Spin diffusion nationallicence Protein NMR nationallicence Juranic Nenad Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic and Foundation, 55905, Rochester, MN, U.S.A aut Zolnai Zsolt Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic and Foundation, 55905, Rochester, MN, U.S.A aut Macura Slobodan Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic and Foundation, 55905, Rochester, MN, U.S.A aut Journal of Biomolecular NMR Kluwer Academic Publishers 9/3(1997-04-01), 317-322 0925-2738 9:3<317 1997 9 10858 https://doi.org/10.1023/A:1018639211400 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1018639211400 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Juranic Nenad Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic and Foundation, 55905, Rochester, MN, U.S.A aut NATIONALLICENCE 700 1- Zolnai Zsolt Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic and Foundation, 55905, Rochester, MN, U.S.A aut NATIONALLICENCE 700 1- Macura Slobodan Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic and Foundation, 55905, Rochester, MN, U.S.A aut NATIONALLICENCE 773 0- Journal of Biomolecular NMR Kluwer Academic Publishers 9/3(1997-04-01), 317-322 0925-2738 9:3<317 1997 9 10858 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer