caa a22 4500 477140629 CHVBK 20180405111731.0 cr unu---uuuuu 170330e19970601xx s 000 0 eng 10.1007/s002850050069 doi (NATIONALLICENCE)springer-10.1007/s002850050069 To treat or not to treat: the case of tuberculosis [Elektronische Daten] [Carlos Castillo-Chavez, Zhilan Feng] . Incomplete treatment of patients with infectious tuberculosis (TB) may not only lead to relapse but also to the development of antibiotic resistant TB - one of the most serious health problems facing society today. In this article, we formulate one-strain and two-strain TB models to determine possible mechanisms that may allow for the survival and spread of naturally resistant strains of TB as well as antibiotic-generated resistant strains of TB. Analysis of our models shows that non-antibiotic co-existence is possible but rare for naturally resistant strains while co-existence is almost the rule for strains that result from the lack of compliance with antibiotic treatment by TB infected individuals. Springer-Verlag Berlin Heidelberg, 1997 Key words: Tuberculosis nationallicence Antibiotic resistance nationallicence Epidemiology nationallicence Co-existence nationallicence Dynamical systems nationallicence Castillo-Chavez Carlos Biometrics Unit, Cornell University, Ithaca, NY 14853, USA, US aut Feng Zhilan Biometrics Unit, Cornell University, Ithaca, NY 14853, USA, US aut https://doi.org/10.1007/s002850050069 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002850050069 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Castillo-Chavez Carlos Biometrics Unit, Cornell University, Ithaca, NY 14853, USA, US aut NATIONALLICENCE 700 1- Feng Zhilan Biometrics Unit, Cornell University, Ithaca, NY 14853, USA, US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer