naa a22 4500 510727840 CHVBK 20180411082942.0 cr unu---uuuuu 180411e20130901xx s 000 0 eng 10.1007/s11748-012-0157-5 doi (NATIONALLICENCE)springer-10.1007/s11748-012-0157-5 Unknown primary large cell neuroendocrine carcinoma (LCNEC) in the mediastinum [Elektronische Daten] [Ai Maeda, Masao Nakata, Kouichiro Yasuda, Takuro Yukawa, Shinsuke Saisho, Riki Okita, Yuji Hirami, Katsuhiko Shimizu] Unknown primary large cell neuroendocrine carcinoma (LCNEC) in the mediastinum is extremely rare. In this report, we present a case of a 53-year-old man with superior vena cava (SVC) syndrome who developed LCNEC in the middle mediastinum. His chief complaint was facial edema. Chest X-ray revealed an abnormal shadow in the right upper mediastinum. Computed tomography (CT) scan of the chest revealed a 67-mm mass in the middle mediastinum. Tumor invasion caused constriction of the SVC. The patient underwent induction chemoradiotherapy with vinorelbin and cisplatin and concurrent radiation therapy. After induction therapy, the tumor size decreased remarkably and was resected completely. The pathological diagnosis was LCNEC. The Japanese Association for Thoracic Surgery, 2012 Mediastinal tumor nationallicence LCNEC nationallicence Induction chemoradiotherapy nationallicence Unknown primary tumor nationallicence Maeda Ai Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut Nakata Masao Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut Yasuda Kouichiro Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut Yukawa Takuro Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut Saisho Shinsuke Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut Okita Riki Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut Hirami Yuji Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut Shimizu Katsuhiko Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut General Thoracic and Cardiovascular Surgery Springer Japan 61/9(2013-09-01), 542-545 1863-6705 61:9<542 2013 61 11748 https://doi.org/10.1007/s11748-012-0157-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11748-012-0157-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Maeda Ai Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut NATIONALLICENCE 700 1- Nakata Masao Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut NATIONALLICENCE 700 1- Yasuda Kouichiro Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut NATIONALLICENCE 700 1- Yukawa Takuro Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut NATIONALLICENCE 700 1- Saisho Shinsuke Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut NATIONALLICENCE 700 1- Okita Riki Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut NATIONALLICENCE 700 1- Hirami Yuji Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut NATIONALLICENCE 700 1- Shimizu Katsuhiko Department of General Thoracic Surgery, Kawasaki Medical School, 577 Matsushima, 701-0192, Kurashiki, Okayama, Japan aut NATIONALLICENCE 773 0- General Thoracic and Cardiovascular Surgery Springer Japan 61/9(2013-09-01), 542-545 1863-6705 61:9<542 2013 61 11748 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer