naa a22 4500 510727859 CHVBK 20180411082942.0 cr unu---uuuuu 180411e20130901xx s 000 0 eng 10.1007/s11748-013-0279-4 doi (NATIONALLICENCE)springer-10.1007/s11748-013-0279-4 Myocardial protection in cardiac surgery: a historical review from the beginning to the current topics [Elektronische Daten] [Hiroshi Yamamoto, Fumio Yamamoto] Myocardial protection has become an essential adjunctive measure in cardiac surgery for a couple of decades, because since the 1950s, the methods of cardioprotection (cardioplegic solutions and related procedures) have been improved by the mechanism of myocardial ischemia/reperfusion-induced damage being unveiled through the untiring efforts of researchers and clinicians. The concept of myocardial protection in cardiac surgery was proposed along with introduction of hypothermic crystalloid potassium cardioplegia in the beginning and has been diversified by pharmacological additives, blood cardioplegia, temperature modulation (warm; tepid), retrograde cardioplegia, controlled reperfusion, integrated cardioplegia, and pre-and postconditioning. This historical review summarized experimental and clinical studies dealing with the methods and results of myocardial protection in cardiac surgery, introducing the newly developed concepts for the last decade and the current topics. The Japanese Association for Thoracic Surgery, 2013 Myocardial protection nationallicence Cardiovascular surgery nationallicence Historical review nationallicence Current topics nationallicence Ischemia nationallicence Reperfusion nationallicence Yamamoto Hiroshi Department of Cardiovascular Surgery, Akita University Graduate School of Medicine and Faculty of Medicine, Hondo 1-1-1, 010-8543, Akita, Akita, Japan aut Yamamoto Fumio Department of Cardiovascular Surgery, Akita University Graduate School of Medicine and Faculty of Medicine, Hondo 1-1-1, 010-8543, Akita, Akita, Japan aut General Thoracic and Cardiovascular Surgery Springer Japan 61/9(2013-09-01), 485-496 1863-6705 61:9<485 2013 61 11748 https://doi.org/10.1007/s11748-013-0279-4 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11748-013-0279-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yamamoto Hiroshi Department of Cardiovascular Surgery, Akita University Graduate School of Medicine and Faculty of Medicine, Hondo 1-1-1, 010-8543, Akita, Akita, Japan aut NATIONALLICENCE 700 1- Yamamoto Fumio Department of Cardiovascular Surgery, Akita University Graduate School of Medicine and Faculty of Medicine, Hondo 1-1-1, 010-8543, Akita, Akita, Japan aut NATIONALLICENCE 773 0- General Thoracic and Cardiovascular Surgery Springer Japan 61/9(2013-09-01), 485-496 1863-6705 61:9<485 2013 61 11748 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer