naa a22 4500 51072793X CHVBK 20180411082942.0 cr unu---uuuuu 180411e20130701xx s 000 0 eng 10.1007/s11748-013-0226-4 doi (NATIONALLICENCE)springer-10.1007/s11748-013-0226-4 Venovenous extracorporeal membrane oxygenation is effective against post-cardiotomy acute respiratory failure in adults [Elektronische Daten] [Hiromasa Nakamura, Hiroki Yamaguchi, Atsushi Amano, Tatsuya Nakao] Background: Acute respiratory failure is a serious issue that occasionally occurs after weaning from cardiopulmonary bypass (CPB) after heart surgery. This condition can be refractory to mechanical ventilation and the mortality rate is high. Venovenous extracorporeal membrane oxygenation (VV-ECMO) is applied to treat acute lung failure after CPB at our institution. This report describes the use of VV-ECMO after cardiac surgery at a single institution. Methods: We analyzed the outcomes of 11 patients who developed severe acute respiratory failure requiring VV-ECMO after undergoing heart surgery with a cardiopulmonary bypass. Results: Four (36.4%) patients died in hospital. One patient required conversion from VV- to venoarterial (VA-) ECMO because of circulatory instability. One patient each died of respiratory failure and heart failure and two died of ischemic colitis. Lung damage secondarily developed in these four patients to other disabled organs. Seven (63.6%) patients whose lungs were primarily disabled were weaned from VV-ECMO upon recovery from respiratory failure and were ambulatory at the time of discharge from hospital. The ratio of PaO2/FIO2 (P/F) at 24h after starting VV-ECMO did not significantly differ between survivors and non-survivors (187.9±57.7 vs. 135.5±20.5, p=0.10), but tended to be higher in survivors. Non-survivors were significantly older than survivors. Conclusion: Patients who develop severe acute respiratory failure after undergoing heart surgery using cardiopulmonary bypass derive a survival benefit from VV-ECMO. The Japanese Association for Thoracic Surgery, 2013 Cardiothoracic surgery nationallicence Extracorporeal membrane oxygenation (ECMO) nationallicence Outcomes nationallicence Nakamura Hiromasa Department of Cardiovascular Surgery, New Tokyo Hospital, 473-1 Nemoto, 271-0077, Matsudo City, Chiba, Japan aut Yamaguchi Hiroki Department of Cardiovascular Surgery, New Tokyo Hospital, 473-1 Nemoto, 271-0077, Matsudo City, Chiba, Japan aut Amano Atsushi Department of Cardiovascular Surgery, Juntendo University, Tokyo, Japan aut Nakao Tatsuya Department of Cardiovascular Surgery, New Tokyo Hospital, 473-1 Nemoto, 271-0077, Matsudo City, Chiba, Japan aut General Thoracic and Cardiovascular Surgery Springer Japan 61/7(2013-07-01), 402-408 1863-6705 61:7<402 2013 61 11748 https://doi.org/10.1007/s11748-013-0226-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11748-013-0226-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nakamura Hiromasa Department of Cardiovascular Surgery, New Tokyo Hospital, 473-1 Nemoto, 271-0077, Matsudo City, Chiba, Japan aut NATIONALLICENCE 700 1- Yamaguchi Hiroki Department of Cardiovascular Surgery, New Tokyo Hospital, 473-1 Nemoto, 271-0077, Matsudo City, Chiba, Japan aut NATIONALLICENCE 700 1- Amano Atsushi Department of Cardiovascular Surgery, Juntendo University, Tokyo, Japan aut NATIONALLICENCE 700 1- Nakao Tatsuya Department of Cardiovascular Surgery, New Tokyo Hospital, 473-1 Nemoto, 271-0077, Matsudo City, Chiba, Japan aut NATIONALLICENCE 773 0- General Thoracic and Cardiovascular Surgery Springer Japan 61/7(2013-07-01), 402-408 1863-6705 61:7<402 2013 61 11748 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer