naa a22 4500 510727956 CHVBK 20180411082942.0 cr unu---uuuuu 180411e20130701xx s 000 0 eng 10.1007/s11748-012-0164-6 doi (NATIONALLICENCE)springer-10.1007/s11748-012-0164-6 An unexpected mortality following cardiac surgery: a post-mortem diagnosis of cardiac amyloidosis [Elektronische Daten] [Gerard Fitzmaurice, Victoria Wishart, Alastair Graham] Amyloidosis is a rare systemic disease that is notoriously difficult to diagnose early. Cardiac involvement is associated with a poor prognosis. We present the case of a 72-year-old gentleman who underwent elective coronary artery bypass grafting and mitral valve repair. While initially making a good post-operative recovery, a sudden deterioration on post-operative day 3 led to an unexpected mortality. Post-mortem examination demonstrated previously undiagnosed severe systemic amyloidosis, which particularly affected his heart, due to underlying multiple myeloma. It is important to emphasise that due to the absence of the typical findings on routine pre-operative investigations suggestive of cardiac amyloidosis in this patient, cardiac surgeons should be aware that symptoms inconsistent with angiography findings should prompt consideration of amyloidosis. Diagnostic tools including cardiac MRI and ultimately endomyocardial biopsy could then facilitate earlier recognition of this enigmatic disease process. The Japanese Association for Thoracic Surgery, 2012 Cardiac surgery nationallicence Amyloid nationallicence Cardiac amyloidosis nationallicence Fitzmaurice Gerard Department of Cardiac Surgery, The Royal Victoria Hospital, Grosvenor Road, BT12 6BA, Belfast, Northern Ireland, UK aut Wishart Victoria Department of Pathology, The Royal Victoria Hospital, Grosvenor Road, BT12 6BA, Belfast, Northern Ireland, UK aut Graham Alastair Department of Cardiac Surgery, The Royal Victoria Hospital, Grosvenor Road, BT12 6BA, Belfast, Northern Ireland, UK aut General Thoracic and Cardiovascular Surgery Springer Japan 61/7(2013-07-01), 417-421 1863-6705 61:7<417 2013 61 11748 https://doi.org/10.1007/s11748-012-0164-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11748-012-0164-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fitzmaurice Gerard Department of Cardiac Surgery, The Royal Victoria Hospital, Grosvenor Road, BT12 6BA, Belfast, Northern Ireland, UK aut NATIONALLICENCE 700 1- Wishart Victoria Department of Pathology, The Royal Victoria Hospital, Grosvenor Road, BT12 6BA, Belfast, Northern Ireland, UK aut NATIONALLICENCE 700 1- Graham Alastair Department of Cardiac Surgery, The Royal Victoria Hospital, Grosvenor Road, BT12 6BA, Belfast, Northern Ireland, UK aut NATIONALLICENCE 773 0- General Thoracic and Cardiovascular Surgery Springer Japan 61/7(2013-07-01), 417-421 1863-6705 61:7<417 2013 61 11748 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer