naa a22 4500 51072812X CHVBK 20180411082942.0 cr unu---uuuuu 180411e20130301xx s 000 0 eng 10.1007/s11748-012-0123-2 doi (NATIONALLICENCE)springer-10.1007/s11748-012-0123-2 A case of successful preoperative chemotherapy with cisplatin and irinotecan followed by curative-intent surgery for locally advanced thymic carcinoma [Elektronische Daten] [Shigeki Suzuki, Hirotoshi Horio, Tai Hato, Masahiko Harada, Yusuke Okuma, Tsunekazu Hishima] The optimal chemotherapy for thymic carcinoma has yet to be determined based on clinical evidence because of the rarity of this pathological entity. We report the case of a patient with locally advanced thymic carcinoma in whom radical excision was achieved with intensive preoperative chemotherapy followed by curative-intent surgery. A 59-year-old woman was diagnosed with Masaoka-Koga stage III thymic cancer showing squamous cell carcinoma histology. Invasion to the ascending aorta and left brachiocephalic vein was suspected from imaging, so preoperative chemotherapy with three cycles of cisplatin and irinotecan was administered. Partial response to chemotherapy was achieved and the residual tumor was completely resected with subsequent surgery. Histopathological examination of the resected specimen demonstrated stage II thymic carcinoma. The patient has shown no evidence of recurrence or surgical complications as of 46months after completing preoperative chemotherapy. The Japanese Association for Thoracic Surgery, 2012 Thymic carcinoma nationallicence Preoperative chemotherapy nationallicence Surgery nationallicence Suzuki Shigeki Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo, 113-8677, Tokyo, Japan aut Horio Hirotoshi Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo, 113-8677, Tokyo, Japan aut Hato Tai Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo, 113-8677, Tokyo, Japan aut Harada Masahiko Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo, 113-8677, Tokyo, Japan aut Okuma Yusuke Department of Respiratory Medicine and Thoracic Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan aut Hishima Tsunekazu Department of Pathology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan aut General Thoracic and Cardiovascular Surgery Springer Japan 61/3(2013-03-01), 166-169 1863-6705 61:3<166 2013 61 11748 https://doi.org/10.1007/s11748-012-0123-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11748-012-0123-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Suzuki Shigeki Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo, 113-8677, Tokyo, Japan aut NATIONALLICENCE 700 1- Horio Hirotoshi Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo, 113-8677, Tokyo, Japan aut NATIONALLICENCE 700 1- Hato Tai Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo, 113-8677, Tokyo, Japan aut NATIONALLICENCE 700 1- Harada Masahiko Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo, 113-8677, Tokyo, Japan aut NATIONALLICENCE 700 1- Okuma Yusuke Department of Respiratory Medicine and Thoracic Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Hishima Tsunekazu Department of Pathology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan aut NATIONALLICENCE 773 0- General Thoracic and Cardiovascular Surgery Springer Japan 61/3(2013-03-01), 166-169 1863-6705 61:3<166 2013 61 11748 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer